A0A9W5S226 · A0A9W5S226_9BACL
- ProteinUvrABC system protein A
- GeneuvrA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids962 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 33-40 | ATP (UniProtKB | ChEBI) | |||
Binding site | 639-646 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | excinuclease repair complex | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | DNA binding | |
Molecular Function | excinuclease ABC activity | |
Molecular Function | zinc ion binding | |
Biological Process | nucleotide-excision repair | |
Biological Process | SOS response |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameUvrABC system protein A
- Short namesUvrA protein
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus
Accessions
- Primary accessionA0A9W5S226
Proteomes
Subcellular Location
Interaction
Subunit
Forms a heterotetramer with UvrB during the search for lesions.
Structure
Family & Domains
Features
Showing features for zinc finger, domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Zinc finger | 252-279 | C4-type | |||
Domain | 604-935 | ABC transporter | |||
Zinc finger | 738-764 | C4-type | |||
Compositional bias | 937-956 | Basic and acidic residues | |||
Region | 937-962 | Disordered | |||
Sequence similarities
Belongs to the ABC transporter superfamily. UvrA family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length962
- Mass (Da)106,558
- Last updated2023-11-08 v1
- MD5 Checksum6E5950348312210B3D930D73880070EA
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 937-956 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JFHU01000110 EMBL· GenBank· DDBJ | EXX89025.1 EMBL· GenBank· DDBJ | Genomic DNA |