A0A9W5S1V2 · A0A9W5S1V2_9BACL
- ProteinEthanolamine ammonia-lyase large subunit
- GeneeutB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids453 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.
Catalytic activity
- ethanolamine = acetaldehyde + NH4+
Cofactor
Note: Binds between the large and small subunits.
Pathway
Amine and polyamine degradation; ethanolamine degradation.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 160-162 | substrate | |||
Binding site | 193 | substrate | |||
Binding site | 194 | adenosylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 246 | adenosylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 287 | substrate | |||
Binding site | 295 | adenosylcob(III)alamin (UniProtKB | ChEBI) | |||
Binding site | 362 | substrate | |||
Binding site | 401 | adenosylcob(III)alamin (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | ethanolamine ammonia-lyase complex | |
Cellular Component | ethanolamine degradation polyhedral organelle | |
Molecular Function | cobalamin binding | |
Molecular Function | ethanolamine ammonia-lyase activity | |
Biological Process | amino acid metabolic process | |
Biological Process | ethanolamine catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEthanolamine ammonia-lyase large subunit
- EC number
- Short namesEAL large subunit
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus
Accessions
- Primary accessionA0A9W5S1V2
Proteomes
Subcellular Location
Interaction
Subunit
The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards.
Structure
Sequence
- Sequence statusComplete
- Length453
- Mass (Da)49,789
- Last updated2023-11-08 v1
- MD5 Checksum825B62D7CDE15FA7D459F71D01819BA4
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JFHU01000133 EMBL· GenBank· DDBJ | EXX88158.1 EMBL· GenBank· DDBJ | Genomic DNA |