A0A9W5RYL7 · A0A9W5RYL7_9BACL

Function

function

Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH2 groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site730Nucleophile
Active site842

GO annotations

AspectTerm
Molecular FunctionABC-type vitamin B12 transporter activity
Molecular Functioncatalytic activity
Molecular Functionpyridoxal phosphate binding
Biological Processcobalamin biosynthetic process
Biological Processglutamine metabolic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cobyric acid synthase

Gene names

    • Name
      cobQ
    • ORF names
      BG53_10495

Organism names

  • Taxonomic identifier
  • Strain
    • CE1
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus

Accessions

  • Primary accession
    A0A9W5RYL7

Proteomes

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain25-354Aminotransferase class I/classII large
Domain385-612CobQ/CobB/MinD/ParA nucleotide binding
Region621-640Disordered
Domain651-849CobB/CobQ-like glutamine amidotransferase

Sequence similarities

Belongs to the CobB/CobQ family. CobQ subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    907
  • Mass (Da)
    98,912
  • Last updated
    2023-11-08 v1
  • MD5 Checksum
    1A3C320A24AFD6639C2E885426D12348
MLEQYGHGGDLLTAQRLYGRDAGEFLDFSSNMNPLGPPQAVLSAVAAFGADIARYPDPASRLLTKRLVERHGIVEANVLIGNGAAELIDLAVRVLRPAAAAIPAPSFAEYGDAVRKVGGTVVPVPLRADNGFDVDETAIRHVLSKHGKPSLWFFGSPNNPTGRLCDPQLVRRLVEEGHMVVLDEAFIDFLPDADRLSLIRFACETPRLIVLRSMTKLYAVPGIRLGYAAGHPDMIAAMRDLQVPWSVNSLAQAIGEAVLGDRAFVERTTAWLQAERPYLAGRLSRLGLRVIPGSANYILFELPAETGMTAADLQRSMGRRGVLIRDASHFAGLSAGYCRVAVKLRADNDRLAETLEACLGGPQPGEPVYIDAPDTFDLPRPARTLMIQGTASDVGKSILTTALCRIFAQDGLRTAPFKSQNMSLNSYVTWDGKEIGVAQGMQADACGTPAVTDMNPILLKPTGHMASQVVVHGVPLRDYDARSYREQYLSEAEPIVQEALARLRQCYDVVVLEGAGSPAEVNLKDRDIVNMRMAGWAGAPVLLVADIDRGGVFASIVGTMDILEPHERERVAGFIINKFRGDAKLLTPGIEWLEKRTGKPVLGVIPHLDALGLEDEDSLSLDGRRRSAAPMTPEKHGGAEDEIAVSGQKLDIAVIRLPRISNFTDFDPLHYERDVSVRYVTDADSLGKPDAVMLPGSKNTAEDMRFLRDSGMAAAVDRYVCGGGVAVGLCGGYEMMGRLLLDPDGIESGHAETAGFGWFPFRVRFERKKRTVRVNGTAALPGWSGRLPVIGYEIHMGRIIHDEPSIQPFTLQEAVIGSTEPPAPYPEGVSSADGRLWGTFMHGALHNDDFRRSWLNGLRETKGWPPLPASLRFRERREAAFDRLAEHVRRHLDVPRIRAIAGLEDKL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JFHU01000264
EMBL· GenBank· DDBJ
EXX84751.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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