A0A9R1PRY0 · A0A9R1PRY0_TRITD
- ProteinGlyceraldehyde-3-phosphate dehydrogenase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids400 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Essential for the maintenance of cellular ATP levels and carbohydrate metabolism.
Catalytic activity
- D-glyceraldehyde 3-phosphate + NADP+ + phosphate = (2R)-3-phospho-glyceroyl phosphate + H+ + NADPH
Pathway
Carbohydrate biosynthesis; Calvin cycle.
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 74-75 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: RI | ||||||
Binding site | 99 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 144 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 186 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 216-218 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: SCT | ||||||
Active site | 217 | Nucleophile | ||||
Sequence: C | ||||||
Site | 244 | Activates thiol group during catalysis | ||||
Sequence: H | ||||||
Binding site | 247 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 275-276 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: TG | ||||||
Binding site | 298 | D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 380 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: N |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | apoplast | |
Cellular Component | chloroplast | |
Molecular Function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | glucose metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlyceraldehyde-3-phosphate dehydrogenase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Pooideae > Triticodae > Triticeae > Triticinae > Triticum
Accessions
- Primary accessionA0A9R1PRY0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 65-217 | Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding | ||||
Sequence: LKVAINGFGRIGRNFLRCWHGRGDSSPLEVIAINDTGGVKQASHLLKYDSTLGIFDADVKPVGDNAISVDGKVIKVVSDRNPSNLPWGEMGIDLVIEGTGVFVDRAGAGKHLEAGAKKVLITAPGKGDIPTYVCGVNADLYTHADTIISNASC |
Sequence similarities
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length400
- Mass (Da)42,643
- Last updated2023-09-13 v1
- Checksum4BE623472664E48D
Computationally mapped potential isoform sequences
There are 23 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A9R1PRR2 | A0A9R1PRR2_TRITD | TRITD_2Bv1G162160 | 411 | ||
A0A9R1RP58 | A0A9R1RP58_TRITD | TRITD_2Bv1G162160 | 405 | ||
A0A9R1RP13 | A0A9R1RP13_TRITD | TRITD_2Bv1G162160 | 139 | ||
A0A9R1RP63 | A0A9R1RP63_TRITD | TRITD_2Bv1G162160 | 373 | ||
A0A9R1RP17 | A0A9R1RP17_TRITD | TRITD_2Bv1G162160 | 397 | ||
A0A9R1RP24 | A0A9R1RP24_TRITD | TRITD_2Bv1G162160 | 385 | ||
A0A9R1RPB3 | A0A9R1RPB3_TRITD | TRITD_2Bv1G162160 | 310 | ||
A0A9R1RPA7 | A0A9R1RPA7_TRITD | TRITD_2Bv1G162160 | 251 | ||
A0A9R1RNS1 | A0A9R1RNS1_TRITD | TRITD_2Bv1G162160 | 229 | ||
A0A9R1PRT1 | A0A9R1PRT1_TRITD | TRITD_2Bv1G162160 | 205 | ||
A0A9R1PRT5 | A0A9R1PRT5_TRITD | TRITD_2Bv1G162160 | 378 | ||
A0A9R1PRT8 | A0A9R1PRT8_TRITD | TRITD_2Bv1G162160 | 381 | ||
A0A9R1PRP9 | A0A9R1PRP9_TRITD | TRITD_2Bv1G162160 | 400 | ||
A0A9R1PRR9 | A0A9R1PRR9_TRITD | TRITD_2Bv1G162160 | 370 | ||
A0A9R1PRU7 | A0A9R1PRU7_TRITD | TRITD_2Bv1G162160 | 368 | ||
A0A9R1PRU8 | A0A9R1PRU8_TRITD | TRITD_2Bv1G162160 | 408 | ||
A0A9R1PS03 | A0A9R1PS03_TRITD | TRITD_2Bv1G162160 | 352 | ||
A0A9R1PS16 | A0A9R1PS16_TRITD | TRITD_2Bv1G162160 | 240 | ||
A0A9R1PSE5 | A0A9R1PSE5_TRITD | TRITD_2Bv1G162160 | 364 | ||
A0A9R1PSF5 | A0A9R1PSF5_TRITD | TRITD_2Bv1G162160 | 401 | ||
A0A9R1PRW4 | A0A9R1PRW4_TRITD | TRITD_2Bv1G162160 | 374 | ||
A0A9R1PSU9 | A0A9R1PSU9_TRITD | TRITD_2Bv1G162160 | 365 | ||
A0A9R1PTP7 | A0A9R1PTP7_TRITD | TRITD_2Bv1G162160 | 341 |
Keywords
- Technical term