A0A9R1CYW3 · A0A9R1CYW3_9TREE
- ProteinRhodanese domain-containing protein
- GeneUBA4
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids408 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 57 | ATP (UniProtKB | ChEBI) | |||
Binding site | 78 | ATP (UniProtKB | ChEBI) | |||
Binding site | 85-89 | ATP (UniProtKB | ChEBI) | |||
Binding site | 102 | ATP (UniProtKB | ChEBI) | |||
Binding site | 146-147 | ATP (UniProtKB | ChEBI) | |||
Binding site | 192 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 195 | Zn2+ (UniProtKB | ChEBI) | |||
Active site | 208 | Glycyl thioester intermediate; for adenylyltransferase activity | |||
Binding site | 266 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 269 | Zn2+ (UniProtKB | ChEBI) | |||
Active site | 362 | Cysteine persulfide intermediate; for sulfurtransferase activity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | adenylyltransferase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | thiosulfate sulfurtransferase activity | |
Molecular Function | URM1 activating enzyme activity | |
Biological Process | protein urmylation | |
Biological Process | tRNA wobble position uridine thiolation |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameRhodanese domain-containing protein
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex
Accessions
- Primary accessionA0A9R1CYW3
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-20 | Disordered | |||
Domain | 314-406 | Rhodanese | |||
Sequence similarities
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length408
- Mass (Da)43,965
- Last updated2023-09-13 v1
- ChecksumFF6B342365F18443
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VHDQ01000012 EMBL· GenBank· DDBJ | KAE8538618.1 EMBL· GenBank· DDBJ | Genomic DNA |