A0A9R1CYW3 · A0A9R1CYW3_9TREE

  • Protein
    Rhodanese domain-containing protein
  • Gene
    UBA4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.

Features

Showing features for binding site, active site.

140850100150200250300350400
Type
IDPosition(s)Description
Binding site57ATP (UniProtKB | ChEBI)
Binding site78ATP (UniProtKB | ChEBI)
Binding site85-89ATP (UniProtKB | ChEBI)
Binding site102ATP (UniProtKB | ChEBI)
Binding site146-147ATP (UniProtKB | ChEBI)
Binding site192Zn2+ (UniProtKB | ChEBI)
Binding site195Zn2+ (UniProtKB | ChEBI)
Active site208Glycyl thioester intermediate; for adenylyltransferase activity
Binding site266Zn2+ (UniProtKB | ChEBI)
Binding site269Zn2+ (UniProtKB | ChEBI)
Active site362Cysteine persulfide intermediate; for sulfurtransferase activity

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionadenylyltransferase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionthiosulfate sulfurtransferase activity
Molecular FunctionURM1 activating enzyme activity
Biological Processprotein urmylation
Biological ProcesstRNA wobble position uridine thiolation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Rhodanese domain-containing protein

Gene names

    • Name
      UBA4
    • ORF names
      D1P53_004980

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MF34
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex

Accessions

  • Primary accession
    A0A9R1CYW3

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-20Disordered
Domain314-406Rhodanese

Sequence similarities

In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    408
  • Mass (Da)
    43,965
  • Last updated
    2023-09-13 v1
  • Checksum
    FF6B342365F18443
MQLTHEASSSRRTAVEGLPLEPEEYERYGRQMIMPDFGLPGQVNLKNAKVAVVGAGGLGCPVLQYLAGAGVGTIGIIDHDTVSMSNLHRQILHTTDRVGVNKAESACQVLRALNNKINLIPHPVPVTPSTALDLLRPYSMVLDCTDRPLTRYLLSDAAVRLDVPLISGAAISSAGQWAVYGGKTKSGKRRACYRCIWPSILPGSVKTCDEQGVWGVVTGMVGIGMAGEAIKLIVGKEDPEPLLHLHHLGSNPLIRTIRIKPPSAKCITCGPNATITDDLDVFGYESFCAGGPETNDETGLIAGQNNHRISVHLDKSKVTVIDTRPQVEFGICSIPGSINMPLPTILSNPSEVQLTPDVIFICRRGNDSQIAASALRKALDSKEDVRVRDVRGGLKAWSREIDVNFPVY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VHDQ01000012
EMBL· GenBank· DDBJ
KAE8538618.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help