A0A9R1CM74 · A0A9R1CM74_9TREE
- ProteinSerine/threonine-protein kinase RIO1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids616 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 214 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 287 | ATP (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Active site | 331 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 336 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Active site | 348 | 4-aspartylphosphate intermediate | ||||
Sequence: D | ||||||
Binding site | 348 | Mg2+ (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | ribosome biogenesis |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSerine/threonine-protein kinase RIO1
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex
Accessions
- Primary accessionA0A9R1CM74
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-94 | Disordered | ||||
Sequence: MSRRPDHGYIDQASEDPVNIVSAPIEDLSQVPHGEQEAEGLNEDSGSSIEEESEGEPFDDEDGGDFDFSVLDVGGSGEEEEEEEDDGDWDVDDE | ||||||
Compositional bias | 44-67 | Acidic residues | ||||
Sequence: DSGSSIEEESEGEPFDDEDGGDFD | ||||||
Compositional bias | 74-94 | Acidic residues | ||||
Sequence: GGSGEEEEEEEDDGDWDVDDE | ||||||
Compositional bias | 111-149 | Polar residues | ||||
Sequence: RQQHAATSGSAPLPARNLSQQTKSKLSKSNPTAGSGVVT | ||||||
Region | 111-169 | Disordered | ||||
Sequence: RQQHAATSGSAPLPARNLSQQTKSKLSKSNPTAGSGVVTNPKAAQDKHDKDKSDRATQE | ||||||
Compositional bias | 153-169 | Basic and acidic residues | ||||
Sequence: AAQDKHDKDKSDRATQE | ||||||
Domain | 161-394 | RIO kinase | ||||
Sequence: DKSDRATQEQVLDGRTRLVLAGLVNRGIIGMIERCISTGKEANVYYSSPGRAVKIYRTSILVFRARQNYIVGEQRFRGEYTSSRNPRKMIRVWAEKELRNLRRLVQGGVRAPVVHECKENVLVMDFLGKGEVASPRLKDADIPEDRLPDLYAELIIATRRMYQHCHLVHADLSEYNILLHDNHLYIIDVSQSVEHDHPRAFDFLRSDISNIEEFFSRRGVATLGIRRSWEFIVT | ||||||
Compositional bias | 485-544 | Basic and acidic residues | ||||
Sequence: SANAKEREKESASAGVDVNDKDEHVGVDESVEKGKKGKSQSKDEEGKSKKSTKSVRFEDG | ||||||
Region | 485-616 | Disordered | ||||
Sequence: SANAKEREKESASAGVDVNDKDEHVGVDESVEKGKKGKSQSKDEEGKSKKSTKSVRFEDGVNEQDEEDDAQKAEEGDEEEGMDKKSRGFRHEDRESKKERKKAVKEEQREKRKTKMPKAEKQKLIKKSASRH | ||||||
Compositional bias | 545-560 | Acidic residues | ||||
Sequence: VNEQDEEDDAQKAEEG | ||||||
Compositional bias | 561-608 | Basic and acidic residues | ||||
Sequence: DEEEGMDKKSRGFRHEDRESKKERKKAVKEEQREKRKTKMPKAEKQKL |
Sequence similarities
Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length616
- Mass (Da)69,263
- Last updated2023-09-13 v1
- ChecksumBA671CCD8C7C6C0E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 44-67 | Acidic residues | ||||
Sequence: DSGSSIEEESEGEPFDDEDGGDFD | ||||||
Compositional bias | 74-94 | Acidic residues | ||||
Sequence: GGSGEEEEEEEDDGDWDVDDE | ||||||
Compositional bias | 111-149 | Polar residues | ||||
Sequence: RQQHAATSGSAPLPARNLSQQTKSKLSKSNPTAGSGVVT | ||||||
Compositional bias | 153-169 | Basic and acidic residues | ||||
Sequence: AAQDKHDKDKSDRATQE | ||||||
Compositional bias | 485-544 | Basic and acidic residues | ||||
Sequence: SANAKEREKESASAGVDVNDKDEHVGVDESVEKGKKGKSQSKDEEGKSKKSTKSVRFEDG | ||||||
Compositional bias | 545-560 | Acidic residues | ||||
Sequence: VNEQDEEDDAQKAEEG | ||||||
Compositional bias | 561-608 | Basic and acidic residues | ||||
Sequence: DEEEGMDKKSRGFRHEDRESKKERKKAVKEEQREKRKTKMPKAEKQKL |