A0A9R1CLH0 · A0A9R1CLH0_9TREE
- Proteinalpha-amylase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids532 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
Cofactor
Features
Showing features for binding site, active site, site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 103 | substrate | ||||
Sequence: W | ||||||
Binding site | 141 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 142 | substrate | ||||
Sequence: H | ||||||
Binding site | 182 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 195 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 224 | substrate | ||||
Sequence: R | ||||||
Active site | 226 | Nucleophile | ||||
Sequence: D | ||||||
Binding site | 226 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 230 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Active site | 250 | Proton donor | ||||
Sequence: E | ||||||
Binding site | 250 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 254 | substrate | ||||
Sequence: G | ||||||
Binding site | 318 | substrate | ||||
Sequence: D | ||||||
Site | 318 | Transition state stabilizer | ||||
Sequence: D | ||||||
Binding site | 365 | substrate | ||||
Sequence: R |
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | alpha-amylase activity | |
Molecular Function | calcium ion binding | |
Biological Process | carbohydrate catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namealpha-amylase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex
Accessions
- Primary accessionA0A9R1CLH0
Proteomes
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-21 | |||||
Sequence: MLAHQAALALIPLLSFLPAYA | ||||||
Chain | PRO_5040147611 | 22-532 | alpha-amylase | |||
Sequence: LDANAMRSRSVYQVITDRFARNSSSTGDCNVADRKYCGGTWSALAEKLDYIQGMGFDTVWISPVVENIGGTTGEGEAYHGYWTLDPESLNSNFGSADELKSLSSSLHNRGMYLQVDVVINHVAATSSSTFQPSGAYGPFSASDDYHPFCWITDYNNQTNVEQCWLGDDSVALADLNTESDTVVSYWNNWIKELVSNYTVDAIRIDTVKHVRQGFWPDFVNAAGVFNQGEVLLGDAPYVAGYQKNASVNPFNYPIYYPLVRAFNGTGQSFNELISMVSSVNGNFTDPTLLGSFLNNHDNARFESIVTDTSLIKNAQAYPLVTDGIPYVYYGSEAGFKGGNDPDNREPMWTTNYDTTSDMYKFFTSLNAARSAAGNASSTFYTDKMTLSQPSETTLLVAKKPLMSVFSNGGSSASNVSVSVDSSSSGWAASTKVIDTLTCESFTTDGSGNLAVTISKGEPRVLIEDSQKGSLCSGSSSSSSSSSKDSGAGMTTRVGGWVALAGIFVAGLQALL | ||||||
Disulfide bond | 50↔58 | |||||
Sequence: CNVADRKYC | ||||||
Disulfide bond | 170↔184 | |||||
Sequence: CWITDYNNQTNVEQC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 34-390 | Glycosyl hydrolase family 13 catalytic | ||||
Sequence: QVITDRFARNSSSTGDCNVADRKYCGGTWSALAEKLDYIQGMGFDTVWISPVVENIGGTTGEGEAYHGYWTLDPESLNSNFGSADELKSLSSSLHNRGMYLQVDVVINHVAATSSSTFQPSGAYGPFSASDDYHPFCWITDYNNQTNVEQCWLGDDSVALADLNTESDTVVSYWNNWIKELVSNYTVDAIRIDTVKHVRQGFWPDFVNAAGVFNQGEVLLGDAPYVAGYQKNASVNPFNYPIYYPLVRAFNGTGQSFNELISMVSSVNGNFTDPTLLGSFLNNHDNARFESIVTDTSLIKNAQAYPLVTDGIPYVYYGSEAGFKGGNDPDNREPMWTTNYDTTSDMYKFFTSLNAAR | ||||||
Region | 486-507 | Disordered | ||||
Sequence: SQKGSLCSGSSSSSSSSSKDSG | ||||||
Compositional bias | 488-507 | Polar residues | ||||
Sequence: KGSLCSGSSSSSSSSSKDSG |
Sequence similarities
Belongs to the glycosyl hydrolase 13 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length532
- Mass (Da)57,191
- Last updated2023-09-13 v1
- Checksum9C47A9A46AFBB10A
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 488-507 | Polar residues | ||||
Sequence: KGSLCSGSSSSSSSSSKDSG |