A0A9R1CG67 · A0A9R1CG67_9TREE
- ProteinPhosphomannomutase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids259 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Catalytic activity
- alpha-D-mannose 1-phosphate = D-mannose 6-phosphate
Cofactor
Pathway
Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 32 | Nucleophile | |||
Binding site | 32 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Active site | 34 | Proton donor/acceptor | |||
Binding site | 34 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 41 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 144 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 155 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 162 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 200 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 202 | alpha-D-mannose 1-phosphate (UniProtKB | ChEBI) | |||
Binding site | 231 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 233 | Mg2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 236 | Mg2+ 1 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | metal ion binding | |
Molecular Function | phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process | |
Biological Process | mannose metabolic process | |
Biological Process | protein N-linked glycosylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphomannomutase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex
Accessions
- Primary accessionA0A9R1CG67
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length259
- Mass (Da)29,062
- Last updated2023-09-13 v1
- MD5 Checksum241DCB0AE06CD7A0B50A5F73794F0319
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
VHDQ01000011 EMBL· GenBank· DDBJ | KAE8539147.1 EMBL· GenBank· DDBJ | Genomic DNA |