A0A9R1CG67 · A0A9R1CG67_9TREE

Function

function

Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site32Nucleophile
Binding site32Mg2+ 1 (UniProtKB | ChEBI)
Active site34Proton donor/acceptor
Binding site34Mg2+ 1 (UniProtKB | ChEBI)
Binding site41alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site144alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site155alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site162alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site200alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site202alpha-D-mannose 1-phosphate (UniProtKB | ChEBI)
Binding site231Mg2+ 1 (UniProtKB | ChEBI)
Binding site233Mg2+ 1 (UniProtKB | ChEBI)
Binding site236Mg2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionmetal ion binding
Molecular Functionphosphomannomutase activity
Biological ProcessGDP-mannose biosynthetic process
Biological Processmannose metabolic process
Biological Processprotein N-linked glycosylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphomannomutase
  • EC number

Gene names

    • ORF names
      D1P53_004236

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MF34
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex

Accessions

  • Primary accession
    A0A9R1CG67

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the eukaryotic PMM family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    259
  • Mass (Da)
    29,062
  • Last updated
    2023-09-13 v1
  • MD5 Checksum
    241DCB0AE06CD7A0B50A5F73794F0319
MSVPQPASATVFPPNIKPFAQRKFPKTICMFDVDGTLSLARQSATPEMFATLRKLRENCAIAFVGGSDLTKILEQVGGEQGLSNFDYGFAENGLIAYKLGQQLDSASFIKHVGEEEYKKLVNWILRYLSEVDIPIKRGTFVEFRNGMINVSPIGRNASIQERIDFEKYDKEHGIRADMVTKLEQEFLHLGLTYSVGGQISFDVFPKGEVGTRPMRLGILRTYKGGNDYEIFSDPRTIGHTVTSPEHTMRLIDELFLTAP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VHDQ01000011
EMBL· GenBank· DDBJ
KAE8539147.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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