A0A9R1CFS8 · A0A9R1CFS8_9TREE

Function

function

Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for active site.

113791002003004005006007008009001,0001,1001,2001,300
TypeIDPosition(s)Description
Active site1107Nucleophile
Active site1225Proton acceptor

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionlysophospholipase activity
Biological Processlipid catabolic process
Biological Processphosphatidylcholine metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lysophospholipase NTE1
  • EC number
  • Alternative names
    • Intracellular phospholipase B

Gene names

    • ORF names
      D1P53_005272

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MF34
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex

Accessions

  • Primary accession
    A0A9R1CFS8

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane12-30Helical
Transmembrane62-82Helical

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain, motif.

TypeIDPosition(s)Description
Region296-381Disordered
Compositional bias334-375Polar residues
Region597-627Disordered
Domain709-810Cyclic nucleotide-binding
Domain1074-1238PNPLA
Motif1078-1083GXGXXG
Motif1105-1109GXSXG
Motif1225-1227DGA/G

Sequence similarities

Belongs to the NTE family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,379
  • Mass (Da)
    151,779
  • Last updated
    2023-09-13 v1
  • Checksum
    E0EBE27688483CE2
MSSIPTPPDANGNPLIALAVAVIYAILYVLQGVKYGVSLLTIGIPSFMVRMLQYSLTISLGFPHLLALFAGVLLALFFLIRYRYLTRYAQLKESALPPPSPPALSSRLLPLDGDGLGLPDSRSQTSSFHNYLDDFLSAIRVFGYLEKPVFHELSRHLQTRRLAAGDTLEIGGGEFWCVVEGKVQVFAPDASPQGTPTPSSDTNTPIRPSFNGYHLLNEVSTGGTLSSLFSILSLFTEDIKLSWRNSTDEEGEEEQIFQGVAEQSSAKLRVKRANSDVSQLGPDSIGIRAIDSASLPESIDGHRDTNTSRSCRERSSSIDAAGETVRRREGIHSSASLPLSSTEPSSPRRSQSLRSSPRLNSATNLLSSQSEHLRSSMPRKAGVEIGSKALKGTIARATEDTTLAVIPAAAFRKLTRKFPKASGTVVQVVLERFSRVTFMTAHKYLGLTREILQTESSLNRLVTHPLPRSFYTGGGMQALRERFQPEARAKGSINYDSMKSSPNARVSSKDYFNYVPESPTVKAPSLPAMTPKPFSPITHKTPLGQTATTPAKNECHNGSASVPSFNLSTASAISPDASLRHALVLCDRCALETSLPVRSTNSNQENPNSTKGSQNGQSSFGSSSERPFKTALGLDTSKRKGLDDGSKKEETLFTVKPGGIAGYLSSLCCTDSYVDITAKTDCFVGFLPHHTLERIIERRPIVLLTLAKRLLSLLSPLVLHIDAALDWQQLNAGQVLYEKGDKSTDFYIVINGRLRAFTEKDGNMHVLREYGQNDSIGELDVITAVDRSDTVHAIRDSELVRIPAALFDAISIKHPETTIQFMRLIAGRVRRALGDETNGRVPGLPTTDMNLKTVCVLGSTRNVPVAQFAGKLKNALEEIGASTSYLDQATVMRHLGRHAFARIGKLKVAGWLADQEQHYRTVLYVADSPPASQWTLTCIRQADLVLIVSMGDDPSLGEYEKLLLATKTTARKELILLHDERTVAPGSTRQWLSNRPWIQTHYHVELPGVVTPARPIPPVHDAAAIAAFKHLREQVETRIKKYRRLRPFTRPRRPAHMNDFARIARRLCGQQIGLVLGGGGARGISHIGMLQALEEFGIPIDAIGGCSIGSFVGGLYARETDLLETAGRTKQFSGRMGSMWRILSDVTYPFVSYTTGHEFNRGIYKAFYNTHIEDFWIPFFANSTNITHSRMEVHRTGYAWRYVRASMTLAGLLPPLSDNGNLLVDGGYMDNTPIQPLRENGIRDIIVVDVGSIDDTSPRDYGDSVSGWWIFFNRLNPFYERRVLSMTEVSSRLTYVSSVKTLEGVKATPGCHYIAMPVQQFDTLGGFKRFSEVLEIGLKAGRETLKKWKEEGTLPTGLVDEAKGSKAVQRGNRLRRMSI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias334-375Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VHDQ01000012
EMBL· GenBank· DDBJ
KAE8538904.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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