A0A9R1CD51 · A0A9R1CD51_9TREE

  • Protein
    tRNA (guanine-N(7)-)-methyltransferase
  • Gene
    TRM8
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the formation of N7-methylguanine at position 46 (m7G46) in tRNA.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

tRNA modification; N7-methylguanine-tRNA biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site101S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site124-125S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site168-169S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site188S-adenosyl-L-methionine (UniProtKB | ChEBI)
Active site191
Binding site275-277S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctiontRNA (guanine(46)-N7)-methyltransferase activity
Molecular FunctiontRNA binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (guanine-N(7)-)-methyltransferase
  • EC number
  • Alternative names
    • Transfer RNA methyltransferase 8
    • tRNA (guanine(46)-N(7))-methyltransferase
    • tRNA(m7G46)-methyltransferase

Gene names

    • Name
      TRM8
    • ORF names
      D1P53_006300

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MF34
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus gattii species complex

Accessions

  • Primary accession
    A0A9R1CD51

Proteomes

Subcellular Location

Keywords

  • Cellular component

Interaction

Subunit

Forms a complex with TRM82.

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-28Disordered

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    302
  • Mass (Da)
    33,951
  • Last updated
    2023-09-13 v1
  • Checksum
    168C20F25E25032A
MSKRTREELEMEAGPSTASPGASASPAPVPPVGEVQLLKVPQKRFYRQRAHANVFIDHELEYPKRPELMDWSTHYPAYFSQPNEDGSITPGEKKVEWADVGCGFGGLLMALAPLFPEKLMLGMEIRTSVTKYVNDRIAATRQVQSLLPADSVDTKPGGYQNVSVIKANSMKHMPNFFAKGQLEKIFFLFPDPHFKNRKHKARIITPALLAEYAFVPSIPLYLTSPCNSSINSAPRPETDLHEWMAHHLHAHPLFEYIPTETLSDDPILEAARTATEEGQKVERNKGDKWVACFTRKPDPEED

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
VHDQ01000015
EMBL· GenBank· DDBJ
KAE8537592.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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