A0A9Q4UHN9 · A0A9Q4UHN9_KLEPN
- ProteinAcetylglutamate kinase
- GeneargB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids258 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
Catalytic activity
- N-acetyl-L-glutamate + ATP = N-acetyl-L-glutamyl 5-phosphate + ADP
Pathway
Amino-acid biosynthesis; L-arginine biosynthesis; N2-acetyl-L-ornithine from L-glutamate: step 2/4.
Features
Showing features for site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 8 | Transition state stabilizer | ||||
Sequence: K | ||||||
Binding site | 44-45 | substrate | ||||
Sequence: GG | ||||||
Binding site | 66 | substrate | ||||
Sequence: R | ||||||
Binding site | 158 | substrate | ||||
Sequence: N | ||||||
Binding site | 181-186 | ATP (UniProtKB | ChEBI) | ||||
Sequence: DVSGIL | ||||||
Binding site | 209-211 | ATP (UniProtKB | ChEBI) | ||||
Sequence: IIT | ||||||
Site | 217 | Transition state stabilizer | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | acetylglutamate kinase activity | |
Molecular Function | ATP binding | |
Biological Process | arginine biosynthetic process via ornithine | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetylglutamate kinase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella
Accessions
- Primary accessionA0A9Q4UHN9
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 5-235 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: LIIKLGGVLLDSEEALERLFTALVNYREAYQRPLIIVHGGGCVVDELMKQLNLPVQKKNGLRVTPAEQIDIITGALAGTANKTLLAWAKKHGISSVGLFLGDGDSVKVTQLDAELGHVGLAQPGSPALINTLLAGGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAEKAEQLIEQGIITDGMIVKVNAALDAARALGRPVDIA |
Sequence similarities
Belongs to the acetylglutamate kinase family. ArgB subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length258
- Mass (Da)27,007
- Last updated2023-09-13 v1
- ChecksumF4DBFC33ADD4D42E