A0A9Q4DEU1 · A0A9Q4DEU1_ACTPL

Function

function

Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Pathway

Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site79Zn2+ (UniProtKB | ChEBI)
Binding site239Zn2+ (UniProtKB | ChEBI)
Binding site243Zn2+ (UniProtKB | ChEBI)
Active site266Proton donor

GO annotations

AspectTerm
Molecular Functionmetal ion binding
Molecular FunctionUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Biological Processlipid A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-3-O-acyl-N-acetylglucosamine deacetylase
  • EC number
  • Short names
    UDP-3-O-acyl-GlcNAc deacetylase
  • Alternative names
    • UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase

Gene names

    • Name
      lpxC
    • ORF names
      OYG11_00150

Organism names

Accessions

  • Primary accession
    A0A9Q4DEU1

Proteomes

Structure

3D structure databases

Family & Domains

Sequence similarities

Belongs to the LpxC family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    306
  • Mass (Da)
    34,349
  • Last updated
    2023-09-13 v1
  • Checksum
    EB4C6E185B8FF0A4
MIKQRTLKQATKVTGIGLHSGKKVTLTLRPAPANTGIVYARTDLEPAVYFPASAESIRDTQLCTCMINDDGVRISTVEHLNAAMASLGLDNLIVEVDAPEIPIMDGSASPFIYLLLDAGIEEQDAPKKFIRIRETVRVEEGDKWAEMKPYSKGLKLDFTIDFSHPMISKDVRNFKMELSAENFIHKISRARTFTFMKDVEYLQSIGLALGGSLDNAIVLDEYRILNEEGLRYKDELVKHKMLDSIGDLFMCGYNILGDFSAYKSGHGLNNKLLRAILANENAWEFVTFEDKEQAPEGYRIGEQVFI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAPQFC010000001
EMBL· GenBank· DDBJ
MCY6522666.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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