A0A9Q4DEU1 · A0A9Q4DEU1_ACTPL
- ProteinUDP-3-O-acyl-N-acetylglucosamine deacetylase
- GenelpxC
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids306 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
Catalytic activity
- a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate
Cofactor
Pathway
Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 79 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 239 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 243 | Zn2+ (UniProtKB | ChEBI) | |||
Active site | 266 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity | |
Biological Process | lipid A biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-3-O-acyl-N-acetylglucosamine deacetylase
- EC number
- Short namesUDP-3-O-acyl-GlcNAc deacetylase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pasteurellales > Pasteurellaceae > Actinobacillus
Accessions
- Primary accessionA0A9Q4DEU1
Proteomes
Sequence
- Sequence statusComplete
- Length306
- Mass (Da)34,349
- Last updated2023-09-13 v1
- ChecksumEB4C6E185B8FF0A4
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
JAPQFC010000001 EMBL· GenBank· DDBJ | MCY6522666.1 EMBL· GenBank· DDBJ | Genomic DNA |