A0A9Q3ZQZ2 · A0A9Q3ZQZ2_9RHOB

  • Protein
    DNA polymerase III subunit epsilon
  • Gene
    dnaQ
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

function

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5' exonuclease activity
Molecular FunctionDNA binding
Molecular FunctionDNA-directed DNA polymerase activity
Molecular Functionmetal ion binding
Biological ProcessDNA replication proofreading

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA polymerase III subunit epsilon
  • EC number

Gene names

    • Name
      dnaQ
    • ORF names
      KBY27_16275

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • SZCCDBB064
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Roseobacteraceae > Ruegeria

Accessions

  • Primary accession
    A0A9Q3ZQZ2

Proteomes

Subcellular Location

Interaction

Subunit

DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-185Exonuclease

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    241
  • Mass (Da)
    26,623
  • Last updated
    2023-09-13 v1
  • Checksum
    B886E02F315A76DF
MREIVLDTETTGFDPETGDRIVEIGAVELWNHIATGNTYHQYINPERMMPAEAFGVHGIGPDILEPPQQPEPGQVTLRDKPVFAKVGQAFRDFVADSHLIIHNASFDMKFLNAELRWMGLPEIPFERAIDTLGMARRKFPGSPATLDALCRRFGIDNSNRVLHGALLDAEILAEVYLELIGGKQPDFGLSTVASSGGTGAETAWRPMPRPTPLPARITEAERASHAEFVEKLGENAVWKRA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAGQAF010000010
EMBL· GenBank· DDBJ
MCE8539012.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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