A0A9Q3WKA2 · A0A9Q3WKA2_9RHOB
- ProteinL-aspartate dehydrogenase
- GenenadX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids275 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
Miscellaneous
The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.
Catalytic activity
- L-aspartate + NAD+ + H2O = oxaloacetate + NH4+ + NADH + H+
Pathway
Cofactor biosynthesis; NAD+ biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aspartate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Molecular Function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | |
Biological Process | NAD biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-aspartate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Roseobacteraceae > Ruegeria
Accessions
- Primary accessionA0A9Q3WKA2
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 47-125 | Aspartate/homoserine dehydrogenase NAD-binding | ||||
Sequence: REQAAHAVLGAPVAQALEGLSERPDLLVDCAGHSGLRAHGVAALGAGVEVLTVSVGALADAVFCAELEAAARAGGTRLC | ||||||
Domain | 174-260 | Aspartate dehydrogenase | ||||
Sequence: TAPATHFTGTARAAAQAYPKNANVAAAVALAGAGLDATRAELIADPGAAANIHEIAAEGAFGRFRFQIEGLPLPGNPRSSALTALSL |
Sequence similarities
Belongs to the L-aspartate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length275
- Mass (Da)27,741
- Last updated2023-09-13 v1
- Checksum4305EB3A6D6020ED