A0A9Q2YXJ2 · A0A9Q2YXJ2_RHOHA
- ProteinTranscription termination factor Rho
- Generho
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids676 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent activity, acting on RNA | |
Molecular Function | helicase activity | |
Molecular Function | RNA binding | |
Biological Process | DNA-templated transcription termination |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTranscription termination factor Rho
- EC number
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Prescottella
Accessions
- Primary accessionA0A9Q2YXJ2
Proteomes
Interaction
Subunit
Homohexamer. The homohexamer assembles into an open ring structure.
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-55 | Disordered | ||||
Sequence: MTDTDLIATPVQESPAESAGARAGNSAQTSDAGSREGAVAASTKRADARRGAGLS | ||||||
Compositional bias | 19-36 | Polar residues | ||||
Sequence: AGARAGNSAQTSDAGSRE | ||||||
Region | 90-294 | Disordered | ||||
Sequence: QGGGAAPSAAAAAAPAEAPAPRKERAETRTEAEAPASPAAGETSESGDSEQGGRRSRQRRGSSRRAGAPESGADDAGTPTETAPAESKPAKQAEGKEETREQGREQGKDQSAEDRGERGGRRERGERGDRSQGGERGERSQGGERGERSQGGNGPRGEGRGERRDADDEEGGRGRRGRRFRERRRGRDRGEGGEGREGREPEIRE | ||||||
Compositional bias | 179-234 | Basic and acidic residues | ||||
Sequence: AKQAEGKEETREQGREQGKDQSAEDRGERGGRRERGERGDRSQGGERGERSQGGER | ||||||
Compositional bias | 246-265 | Basic and acidic residues | ||||
Sequence: GEGRGERRDADDEEGGRGRR | ||||||
Compositional bias | 273-294 | Basic and acidic residues | ||||
Sequence: RRGRDRGEGGEGREGREPEIRE | ||||||
Domain | 298-376 | Rho RNA-BD | ||||
Sequence: LQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNLVRKNGLRRGDAITGAVRVPREGEQSNQRQKFNPLVRLDTVNGGE |
Sequence similarities
Belongs to the Rho family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length676
- Mass (Da)72,308
- Last updated2023-09-13 v1
- ChecksumBAA338849C03CE8A
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 19-36 | Polar residues | ||||
Sequence: AGARAGNSAQTSDAGSRE | ||||||
Compositional bias | 179-234 | Basic and acidic residues | ||||
Sequence: AKQAEGKEETREQGREQGKDQSAEDRGERGGRRERGERGDRSQGGERGERSQGGER | ||||||
Compositional bias | 246-265 | Basic and acidic residues | ||||
Sequence: GEGRGERRDADDEEGGRGRR | ||||||
Compositional bias | 273-294 | Basic and acidic residues | ||||
Sequence: RRGRDRGEGGEGREGREPEIRE |
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
WUXR01000018 EMBL· GenBank· DDBJ | MBM4568274.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
MULT01000010 EMBL· GenBank· DDBJ | MBP0099200.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
WVBC01000034 EMBL· GenBank· DDBJ | NKT81570.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
WVDC01000010 EMBL· GenBank· DDBJ | NKW43698.1 EMBL· GenBank· DDBJ | Genomic DNA |