A0A9Q2YXJ2 · A0A9Q2YXJ2_RHOHA

Function

function

Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site.

167650100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site419-424ATP (UniProtKB | ChEBI)
Binding site431-436ATP (UniProtKB | ChEBI)
Binding site462ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent activity, acting on RNA
Molecular Functionhelicase activity
Molecular FunctionRNA binding
Biological ProcessDNA-templated transcription termination

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Transcription termination factor Rho
  • EC number
  • Alternative names
    • ATP-dependent helicase Rho

Gene names

    • Name
      rho
    • ORF names
      B0F69_21270
      , GS441_23500
      , GS882_26220
      , GS947_19450

Organism names

  • Taxonomic identifier
  • Strains
    • PAM2281
    • Lh_17
    • Lh_116_1
    • Lh_16_1
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Mycobacteriales > Nocardiaceae > Prescottella

Accessions

  • Primary accession
    A0A9Q2YXJ2

Proteomes

Interaction

Subunit

Homohexamer. The homohexamer assembles into an open ring structure.

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region1-55Disordered
Compositional bias19-36Polar residues
Region90-294Disordered
Compositional bias179-234Basic and acidic residues
Compositional bias246-265Basic and acidic residues
Compositional bias273-294Basic and acidic residues
Domain298-376Rho RNA-BD

Sequence similarities

Belongs to the Rho family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    676
  • Mass (Da)
    72,308
  • Last updated
    2023-09-13 v1
  • Checksum
    BAA338849C03CE8A
MTDTDLIATPVQESPAESAGARAGNSAQTSDAGSREGAVAASTKRADARRGAGLSGMVLAELRTLAGELGIKGTSGMRKGDLIAAIKERQGGGAAPSAAAAAAPAEAPAPRKERAETRTEAEAPASPAAGETSESGDSEQGGRRSRQRRGSSRRAGAPESGADDAGTPTETAPAESKPAKQAEGKEETREQGREQGKDQSAEDRGERGGRRERGERGDRSQGGERGERSQGGERGERSQGGNGPRGEGRGERRDADDEEGGRGRRGRRFRERRRGRDRGEGGEGREGREPEIREDDVLQPVAGILDVLDNYAFVRTSGYLAGPNDVYVSMNLVRKNGLRRGDAITGAVRVPREGEQSNQRQKFNPLVRLDTVNGGEVEAARKRPEFNKLTPLYPNQRLRLETTPNILTTRVIDLVMPIGKGQRALIVSPPKAGKTTVLQDIANAISVNNPECYLMVVLVDERPEEVTDMQRSVNGEVIASTFDRPPADHTSVAELAIERAKRLVEAGRDVVVLLDSITRLGRAYNNSSPASGRILSGGVDSTALYPPKRFLGAARNIENGGSLTIIASALVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNLSSTRKDELLMSPDEFAIVHKLRRVLSGLDTHQAIDLLVDRLKKSQSNVEFLMTVSKTAPGSLAD

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias19-36Polar residues
Compositional bias179-234Basic and acidic residues
Compositional bias246-265Basic and acidic residues
Compositional bias273-294Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
WUXR01000018
EMBL· GenBank· DDBJ
MBM4568274.1
EMBL· GenBank· DDBJ
Genomic DNA
MULT01000010
EMBL· GenBank· DDBJ
MBP0099200.1
EMBL· GenBank· DDBJ
Genomic DNA
WVBC01000034
EMBL· GenBank· DDBJ
NKT81570.1
EMBL· GenBank· DDBJ
Genomic DNA
WVDC01000010
EMBL· GenBank· DDBJ
NKW43698.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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