A0A9Q0L872 · A0A9Q0L872_ANAIG

Function

function

Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

pyridoxal 5'-phosphate (UniProtKB | Rhea| CHEBI:597326 )

Pathway

Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2.

Features

Showing features for site, binding site.

TypeIDPosition(s)Description
Site74May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate
Binding site75pyridoxal 5'-phosphate (UniProtKB | ChEBI)
Binding site97substrate
Binding site98substrate
Binding site105substrate
Binding site272tRNA (UniProtKB | ChEBI)
Binding site314substrate
Binding site405tRNA (UniProtKB | ChEBI)
Binding site470tRNA (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionO-phosphoseryl-tRNA(Sec) selenium transferase activity
Molecular FunctiontRNA binding
Biological Processconversion of seryl-tRNAsec to selenocys-tRNAsec
Biological Processselenocysteine incorporation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    O-phosphoseryl-tRNA(Sec) selenium transferase
  • EC number
  • Alternative names
    • Selenocysteine synthase
    • Selenocysteinyl-tRNA(Sec) synthase
    • Sep-tRNA:Sec-tRNA synthase

Gene names

    • ORF names
      M0811_02833

Organism names

Accessions

  • Primary accession
    A0A9Q0L872

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue285N6-(pyridoxal phosphate)lysine

Family & Domains

Features

Showing features for coiled coil, compositional bias, region.

TypeIDPosition(s)Description
Coiled coil189-216
Compositional bias507-524Polar residues
Region507-527Disordered

Sequence similarities

Belongs to the SepSecS family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    550
  • Mass (Da)
    61,947
  • Last updated
    2023-09-13 v1
  • Checksum
    93EDA021A9D39B1B
MDLENLKLAAQIISQPYSQRAQDAKKQQIQKVKVLLTQRSLPEKGWNEEEIQPFLCELRMMDSNNYLGHAGVGEREGRIYSSLVYRRNFGFAHGMGRSGDILELQPKAAGGSLVAKLTNSLAMSAIKESGISNIKACVVLPMATGMSIAFSFLALRDIRPKTAKFVIMSRMDHKSCIKSIGTAGFEPVIVEQLLENDELVTDLEEIENQIQKCGSENILAVFTTTSCFAPRTPDKAIEVSMMCKKYNVPHLVNNAYGLQSRKTSAMLNEAIKKGRIDIIVQSTDKNFMVPIGGSIVSSPNKAMIKVISSTYPGRASISPIVDLFITLLQMGRDGFKKLLKKRKKLYSYFTDKVSRVAEKHQERLLKTPNNPISFVMSLKTFDKVDDLDSSKKTLPSMLGSMLFARQCSGSRVINKGVVKEICGIKFQGYGAHSSKYPFSYMAMSCAIGIKKSEIDTFVERLDKALIEFRKFSQNPQRNVPQDLLVYLKHKDQKNHKNIQNFKNSNLNSNQNQNQNQNHQLEDNQLENQIIKEIEKDPKVDYFEINENSQK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias507-524Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAPDFW010000125
EMBL· GenBank· DDBJ
KAJ5067645.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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