A0A9P9LEN4 · A0A9P9LEN4_9HELO

Function

function

Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. Binds RNAs which might negatively affect its histone methyltransferase activity. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3. COMPASS recognizes ubiquitinated H2B on one face of the nucleosome which stimulates the methylation of H3 on the opposing face.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentchromosome
Cellular ComponentSet1C/COMPASS complex
Molecular Functionhistone H3K4 methyltransferase activity
Biological Processmethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Histone-lysine N-methyltransferase, H3 lysine-4 specific
  • EC number

Gene names

    • ORF names
      BKA65DRAFT_559927

Organism names

  • Taxonomic identifier
  • Strain
    • MPI-PUGE-AT-0058
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Helotiales > Helotiales incertae sedis > Rhexocercosporidium

Accessions

  • Primary accession
    A0A9P9LEN4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Component of the COMPASS (Set1C) complex.
Component of the Set1C/COMPASS complex.

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region17-46Disordered
Compositional bias19-33Basic and acidic residues
Compositional bias114-171Polar residues
Region114-184Disordered
Region542-570Disordered
Compositional bias551-570Basic and acidic residues
Region661-688Disordered
Region736-767Disordered
Domain1122-1239SET
Domain1248-1264Post-SET

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,264
  • Mass (Da)
    140,734
  • Last updated
    2023-09-13 v1
  • Checksum
    FB3613860222582D
MSRAPAAGFAQFFPTAPRAAKDKAKEREKVKIFSSQDSPSTRPIADMKVILPKVRIDDAPSRSGEGGVPTADITAPLLDEGDLLNGVGSASSHSSTVSSVFSSAAQHNNLAAASNNNFSTTPMTNVDSSPNHVASPHQHKSAAVGSSSTGFSSEKYLTQNDVPQPQDTAKADTPPTDPRVYARDPNRSVKGCIITYDPLLDKKLSSKDMKKAKPIYKDIGLEEDDAPPADPRLAKRGGKLDYINVDFHNPQSRLRHAPYLLRPYAYDPKTSLGPGPPTQVVVTGFDPLHNFANVAAIFSSFGEIAESSNKLHPENGSCLGFATFRYRDSRIIKGGRFISAIEAAKIAVRKGSSMRIGSSNVKVDFDAEGNKSRRMMENLLKAPKPEPVTQNVKAVSTFAAKPADAAKFSGPPPTAPKGPASSRPIFRPPIQSITPSAILPPTKPKPIRVMPSTEPVSQQLMHQPYIFVSGESVPCMNTTPPHMLKRMRHFNPEDVKMDAFGYYIIFPNSDQARNDCDRCFRTLDRTLMFNYTMIMQPFPWGTSGSRSAAHRATESNRKRSRSPSLKDNEEWERQVAIARRREEAADVEVERKERAMNFDPAREAIEVIRKQLKIQLLKNIREKTAAPVIHTFLDPANHTAKRRKYGIDDPKDMKLQLIYEDDEREESPSVGTPNSRNETFDRRVMGPGRMNISAMPRIRKAKNGAKSSVGFQDPFARARPKSKNIIRGLSSKWIESSPESEDDFRSRARDTEEPDSRPRSRMTSEEDDAYDVFQRSGDARVVDDDSMSEASFVVRDNIPTKKRKLDLQVEAALKRQKKSDEELFGVAREKIDEEFPLSASTIDEEMPDVDSVLGNELDAQAALAEGRRKLAAKKKKKSKRQIFEEREALKKEQEGVYMDTFDHQPSDSPEDDDEEFVTETAPVETTVEWGMSAEVPRPTVDDDFSTILDLDGIQNLIKDDEDIPAAISILKSDGKPKPGWAKSWAWRQEDIKALNRDGYRGLVTTDTTIGGYYVPNASGCARTEGTKKILNAEKSKYLPHRIRVLKRREEREALASRTGRDSAAEAAQAAKIAADKLATKGNSRANRLNQRAIAADLDRQKKSLGTDVDNVLSFNQLKKRKKLVKFARSAIHNWGLYAEEDIAMNDMIIEYVGEKVRQQVADLREHRYLKSGIGSSYLFRIDENTVVDATKKGGIARFINHSCMPNCTAKIITVDKSKRIVIYALRDIAENEELTYDYKFEREIGSTDRIPCLCGTAACKGFLN

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias19-33Basic and acidic residues
Compositional bias114-171Polar residues
Compositional bias551-570Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAGTJL010000030
EMBL· GenBank· DDBJ
KAH7306080.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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