A0A9P7Y9C4 · A0A9P7Y9C4_9HELO

  • Protein
    Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoskeleton
Cellular Componentcytosol
Molecular Function5-diphosphoinositol pentakisphosphate 1-kinase activity
Molecular FunctionATP binding
Molecular Functioninositol hexakisphosphate kinase activity
Biological Processinositol metabolic process
Biological Processinositol phosphate biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase
  • EC number

Gene names

    • ORF names
      BJ875DRAFT_387731

Organism names

  • Taxonomic identifier
  • Strain
    • TRa018bII
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Leotiomycetes > Helotiales > Helotiales incertae sedis > Amylocarpus

Accessions

  • Primary accession
    A0A9P7Y9C4

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain, coiled coil.

Type
IDPosition(s)Description
Region1-323Disordered
Compositional bias7-21Polar residues
Compositional bias29-79Polar residues
Compositional bias109-134Polar residues
Compositional bias184-266Polar residues
Compositional bias303-319Polar residues
Domain340-427VIP1 N-terminal
Domain564-656ATP-grasp fold RimK-type
Region684-708Disordered
Compositional bias692-708Polar residues
Region727-774Disordered
Compositional bias750-768Polar residues
Compositional bias949-968Basic and acidic residues
Region949-972Disordered
Coiled coil1068-1095
Compositional bias1250-1268Basic and acidic residues
Region1250-1290Disordered
Compositional bias1531-1545Basic and acidic residues
Region1531-1583Disordered

Sequence similarities

Belongs to the histidine acid phosphatase family. VIP1 subfamily.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,583
  • Mass (Da)
    173,296
  • Last updated
    2023-09-13 v1
  • MD5 Checksum
    26BE9574770D686A7370D944C0BAB93E
MGPDPDNATVTATSTATSPSPSPSSSPSPSTSPSTATATTTATPAATSIATSSAPPKVKQRTSSNTHHLVSNLNPASNRKGRYADTAMTTMHADRPSISMPPPPSIPRSRTSSSYSIKSSATDTSRQIPILENSARRASQADIAVEDFDPPRLSPGIMTDDPSKFSPLPDAALRSKPSVPDIETKRMSVSSMYSLSSARAGGAPSSTASANGSEGGYNTRATSGTLSPNKPMGGAETSTSAISVTTSSSGPFSNNGSANGPSLTPRETPAHASDMAKRNAAQRGEGAPRSTVPTRSRSRAKRRFSGSTGASSHSPSSDRGDRMYYSKKEEDTKPSLYGVIGVCALDVKARSKPSRNILNRLLANREFEVKVFGDKVILDEDIENWPLCDYLISFYSDGFPLDKAIAYVKTRKPFCVNDVPMQKILWDRRICLMILDKINVPTPKRVEVNRDGGPSLLTPELANVLRETTGVVLIGPDDGTGGQAPMPRQVELVEDGDVLSVDGVYLRKPFIEKPISGEDHNLIVYYPKSQGGGARKLFRKIGNKSSEKVEGMNTPRAILEPSSSYLYEKFMHVDNSEDVKAYTVGPTFCHAETRKSPVVDGLVRRNTHGKEIRYITSLSKEEAAMASRIAVSFGQRVCGFDLLRAEGKSFVIDVNGWSFVKDNDEYYEQCSRILREMFLKERNRRNGHAEDPSSSTSHPSPSDGTISPLSRRDTFKENHRSALQTILSKSPSMSKLHVGHHKKALGHSSPGASSVPTPRTSPPSGADKGSSMPSVPATPMLPPPAVSAPSTTLPSARSSVVASTVAQESISEPNLMDPPAPKHTWKLKGMVSVIRHADRTPKQKYKFTFHTKPFVGLLKGHQEEVLLTGAAALDSVIVAVDLARKEGIEDQQKLRNLRNVLAKKGGWAGTKVQIKPMFRKRLPEEILSTISGLDSSGTGSTKDRVKELAEDFPEGESTNSRDVKRPPTRSDSLSGITLSRITAAENSLVLDKLQLIVKWGGEPTHSARYQSQELGENMRNDLMLMNREVLDEVHVFSSSERRVTTSAQIWASAFTNQPHLPSDFITIRKDLLDDSNAAKDEMDKVKKKLKTLLRQGIEAPPQFAWPTNMPEPSIVQAYVVQLMKFHRRVMRHNYGKLYGGASTSLSAIANPGDKNPSKTDKGQASGPTTSAMAQATATTGIQSRWCCGEDADLFKERWEKLFTEFCDGDKVDPSKISELYDTMKFDALHNRQFLEWVFTPGKSILDEEEEALAAESKGRERGPPRDVGPDDATVDQSQTTPLEKTDTNKSVRHRIFRRRESMMKDSKAVEEQTEQYFKLFTGSGQTKAKTDARLEKLRELYKLAKVLFDFICPQEYGITDHEKLEIGLLTSLPLLKEIVQDLEEMQASDDAKSFIYFTKESHIYTLLNCILEGGVETKIKRSAIPELDYLSQICFELYESENKTPPDAPPGDVAKYAYSIRISISPGAHTFDPLDVQLDSKHCISCAQRRSLTAHGDWKKVIETLRAKFHQVKLPKSFLAVNLSESHTFHKKEELEDKGDPEQKDLSHPLSPGPSSSPTIGIGAAESLPPSSVPSSLDPHPNV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias7-21Polar residues
Compositional bias29-79Polar residues
Compositional bias109-134Polar residues
Compositional bias184-266Polar residues
Compositional bias303-319Polar residues
Compositional bias692-708Polar residues
Compositional bias750-768Polar residues
Compositional bias949-968Basic and acidic residues
Compositional bias1250-1268Basic and acidic residues
Compositional bias1531-1545Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MU251796
EMBL· GenBank· DDBJ
KAG9229252.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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