A0A9P7EG69 · A0A9P7EG69_9AGAM

  • Protein
    PI31 proteasome regulator N-terminal-domain-containing protein
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentproteasome complex
Molecular Functionendopeptidase inhibitor activity
Molecular Functionproteasome binding
Biological Processproteasome-mediated ubiquitin-dependent protein catabolic process

Names & Taxonomy

Protein names

  • Submitted names
    • PI31 proteasome regulator N-terminal-domain-containing protein

Gene names

    • ORF names
      BJ212DRAFT_1297741

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MN1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Boletales > Suillineae > Suillaceae > Suillus

Accessions

  • Primary accession
    A0A9P7EG69

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-27
ChainPRO_504012380728-340

Keywords

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain23-173PI31 proteasome regulator N-terminal
Region177-247Disordered
Compositional bias190-218Pro residues
Domain226-299PI31 proteasome regulator C-terminal
Region276-340Disordered
Compositional bias289-306Pro residues

Sequence similarities

Belongs to the proteasome inhibitor PI31 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    340
  • Mass (Da)
    36,739
  • Last updated
    2023-09-13 v1
  • MD5 Checksum
    E20191D1FB4AD172DD80E10951539063
MANNVLDPSALVGILLNLLPLTNKTLASPHDGLAALVHTAFSALSFRLIATDDTSSAKEHSNNVLPDDWNTKGLVDRTFRYRHDQSGLEFVVKVIKLGQRTLISAIAVENDKSVSLDVATNDFVSPSFYPYDAAKSDAPPLVHGFISSNRITDFISQLKLKIIQKLIPGLRKEGYIEETEDSSSNAGPAPRAENPPPARPRPDSPPYPDDPYHLPPGLRPRNPLEIGRRDLDPFGGINPFQPPSLFPGNGGDGMFVGPDHPIFGMRGNRGQEMRGPWGGDGYLPPMGAPPGARFDPIGPNPGPFNPSFNGRPRRGPPGSGNSRDPDNDEFMPPGAGDMFM

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias190-218Pro residues
Compositional bias289-306Pro residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABBWG010000008
EMBL· GenBank· DDBJ
KAG1820312.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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