A0A9P7DXQ3 · A0A9P7DXQ3_9AGAM

  • Protein
    Methylthioribulose-1-phosphate dehydratase
  • Gene
    MDE1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site100substrate
Binding site118Zn2+ (UniProtKB | ChEBI)
Binding site120Zn2+ (UniProtKB | ChEBI)
Binding site199Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmethylthioribulose 1-phosphate dehydratase activity
Molecular Functionzinc ion binding
Biological ProcessL-methionine salvage from methylthioadenosine
Biological ProcessL-methionine salvage from S-adenosylmethionine

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylthioribulose-1-phosphate dehydratase
  • EC number
  • Short names
    MTRu-1-P dehydratase

Gene names

    • Name
      MDE1
    • ORF names
      BJ212DRAFT_1390527

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MN1
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Boletales > Suillineae > Suillaceae > Suillus

Accessions

  • Primary accession
    A0A9P7DXQ3

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-226Class II aldolase/adducin N-terminal

Sequence similarities

Belongs to the aldolase class II family. MtnB subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    239
  • Mass (Da)
    26,819
  • Last updated
    2023-09-13 v1
  • Checksum
    6EE38269F5BEA67D
MSASTEQEDALVTSTDPLHPANLISELCASFYRLGWVTGTGGGICIRTHDKVYIAPSGVQKERIEPSHIFVLPYPQAEPSPHTDRIFLRRPKLNLKESACTPLFWNAFTIRNASSCIHTHSQNAVMATLLWEKEKMFRISHQKMIKGVRIGGNGPTLSYLDTLEVPIIDNTPNEEDLKDSMKEAMEKYPRAAGILVLRHGIYVWGDDWQKAKTQTECLDYLLEIGVKMKLAGLPTVLNI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JABBWG010000050
EMBL· GenBank· DDBJ
KAG1805804.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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