A0A9P7DXQ3 · A0A9P7DXQ3_9AGAM
- ProteinMethylthioribulose-1-phosphate dehydratase
- GeneMDE1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids239 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
Catalytic activity
- S-methyl-5-thio-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | methylthioribulose 1-phosphate dehydratase activity | |
Molecular Function | zinc ion binding | |
Biological Process | L-methionine salvage from methylthioadenosine | |
Biological Process | L-methionine salvage from S-adenosylmethionine |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethylthioribulose-1-phosphate dehydratase
- EC number
- Short namesMTRu-1-P dehydratase
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Boletales > Suillineae > Suillaceae > Suillus
Accessions
- Primary accessionA0A9P7DXQ3
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 22-226 | Class II aldolase/adducin N-terminal | ||||
Sequence: NLISELCASFYRLGWVTGTGGGICIRTHDKVYIAPSGVQKERIEPSHIFVLPYPQAEPSPHTDRIFLRRPKLNLKESACTPLFWNAFTIRNASSCIHTHSQNAVMATLLWEKEKMFRISHQKMIKGVRIGGNGPTLSYLDTLEVPIIDNTPNEEDLKDSMKEAMEKYPRAAGILVLRHGIYVWGDDWQKAKTQTECLDYLLEIGV |
Sequence similarities
Belongs to the aldolase class II family. MtnB subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length239
- Mass (Da)26,819
- Last updated2023-09-13 v1
- Checksum6EE38269F5BEA67D
Keywords
- Technical term