A0A9P2TX92 · A0A9P2TX92_BRUML

Function

function

Hydrolyzes N-terminal residues in D-amino acid-containing peptides.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Release of an N-terminal D-amino acid from a peptide, Xaa-|-Yaa-, in which Xaa is preferably D-Ala, D-Ser or D-Thr. D-amino acid amides and methyl esters also are hydrolyzed, as is glycine amide.
    EC:3.4.11.19 (UniProtKB | ENZYME | Rhea)

Activity regulation

Inhibited by beta-lactam compounds such as 6-aminopenicillic acid, 7-aminocephalosporanic acid, benzylpenicillin and ampicillin. Inhibited by p-chloromercuribenzoate.

Features

Showing features for active site, binding site.

151850100150200250300350400450500
Type
IDPosition(s)Description
Active site62Nucleophile
Active site65Proton donor/acceptor
Binding site481substrate

GO annotations

AspectTerm
Molecular Functionaminopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    D-aminopeptidase
  • EC number

Gene names

    • Name
      dap
    • ORF names
      P043_02929

Organism names

  • Taxonomic identifier
  • Strain
    • 02-5863-1
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Brucellaceae > Brucella/Ochrobactrum group > Brucella

Accessions

  • Primary accession
    A0A9P2TX92

Proteomes

Interaction

Subunit

Homodimer.

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, region.

Type
IDPosition(s)Description
Domain10-324Beta-lactamase-related
Domain340-516D-aminopeptidase
Region373-392Disordered
Region477-487Important for specificity

Sequence similarities

Belongs to the peptidase S12 family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    518
  • Mass (Da)
    56,887
  • Last updated
    2023-09-13 v1
  • Checksum
    EBC9EA71E2CB3C57
MPNIDLPTLEAFVHAIPQNYKGPGGAVAVVRNGEIVLRHAWGFADLAARKAMTPETRMPICSVSKQFTCAVLLDCIGEPEMLDSALAAYLDQFEDGRPAVRDLCNNQSGLRDYWALTVLCGAAPEGIFLPDQAQNLLRRLKTTHFAPGTHYSYCNGNFRILADLIEQHTGRSLADLLAERIFAPAAMKTAELIPDTALFNECTGYEGDTVRGFLPAINRIHWLGDAGICASLDDMIAWEQFIDRTRHDENGLYRRLSSPQTFADGAPAPYGFGLKFEETGGKRLTGHGGALRGWRCQRWHCADERISTIVMFNFEGNASDAALKMMNAALGIPPAKPVRAQANPGWFGSWLNPETGLVLSLEDAGGGRMKARFGTGPEKMDISGENEAQSSMTTLRRDGDMIHLARKDENLHLAMHRLKGKARQDIAGRYRSDELEADLLLVSEGGAIYGAFEGFLGKSDMYPLYAAGPDVWLLPVQRSMDAPSPGEWKLVFHRDAAGRITGVTVGCWLARGVEYKRL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AXMZ01000009
EMBL· GenBank· DDBJ
ERU21955.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help