A0A9P1BRY1 · A0A9P1BRY1_9DINO
- ProteinNAD(P)H-hydrate epimerase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids473 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
Catalytic activity
- (6R)-NADHX = (6S)-NADHX
Cofactor
Note: Binds 1 potassium ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 99-103 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 100 | K+ (UniProtKB | ChEBI) | |||
Binding site | 162 | K+ (UniProtKB | ChEBI) | |||
Binding site | 166-172 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 194 | (6S)-NADPHX (UniProtKB | ChEBI) | |||
Binding site | 197 | K+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | metal ion binding | |
Molecular Function | NADHX epimerase activity | |
Molecular Function | nucleotide binding |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD(P)H-hydrate epimerase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Sar > Alveolata > Dinophyceae > Suessiales > Symbiodiniaceae > Cladocopium
Accessions
- Primary accessionA0A9P1BRY1
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Family & Domains
Features
Showing features for domain, compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 46-253 | YjeF N-terminal | |||
Compositional bias | 292-311 | Basic and acidic residues | |||
Region | 292-317 | Disordered | |||
Sequence similarities
Belongs to the NnrE/AIBP family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length473
- Mass (Da)51,456
- Last updated2023-09-13 v1
- Checksum151068C4EB7F86CD
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 292-311 | Basic and acidic residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CAMXCT010000355 EMBL· GenBank· DDBJ | CAI3977620.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CAMXCT020000355 EMBL· GenBank· DDBJ | CAL1130995.1 EMBL· GenBank· DDBJ | Genomic DNA |