A0A9P1BRY1 · A0A9P1BRY1_9DINO

  • Protein
    NAD(P)H-hydrate epimerase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site99-103(6S)-NADPHX (UniProtKB | ChEBI)
Binding site100K+ (UniProtKB | ChEBI)
Binding site162K+ (UniProtKB | ChEBI)
Binding site166-172(6S)-NADPHX (UniProtKB | ChEBI)
Binding site194(6S)-NADPHX (UniProtKB | ChEBI)
Binding site197K+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrion
Molecular Functionmetal ion binding
Molecular FunctionNADHX epimerase activity
Molecular Functionnucleotide binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD(P)H-hydrate epimerase
  • EC number
  • Alternative names
    • NAD(P)HX epimerase

Gene names

    • ORF names
      C1SCF055_LOCUS5749

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Sar > Alveolata > Dinophyceae > Suessiales > Symbiodiniaceae > Cladocopium

Accessions

  • Primary accession
    A0A9P1BRY1

Subcellular Location

Family & Domains

Features

Showing features for domain, compositional bias, region.

Type
IDPosition(s)Description
Domain46-253YjeF N-terminal
Compositional bias292-311Basic and acidic residues
Region292-317Disordered

Sequence similarities

Belongs to the NnrE/AIBP family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    473
  • Mass (Da)
    51,456
  • Last updated
    2023-09-13 v1
  • Checksum
    151068C4EB7F86CD
MREQWKRESMARKWRCWVHWVKHRSTVLSGIPRQGACGRLLNQKEAIAVDEELMASPGFSVDQLMELAGLSVACAVATAFPREQYSTNPAVLLVCGPGNNGGDGLVAARHLHHFGYAPHVIYPKANQKSQLFVNLTTQLAQLSVPVEAALPENLERYCVVVDAIFGFSFSGAVRAPFDEIIRRLSSGPPVLSVDIPSGWDVEQGPPAEGVTLQPGFLISLTAPKMCAAHFKGRHFLGGRFALNDLERANAELGALLPQLRQACQGLSVVREAQAQGVCASELVPGHLPNEEVEARHGHRAGGKDVVPDDALHPLARPRQAPAAAKWDWVGTKGRVRAQGPCWRPSCPSPDSCNAGAGCPVHLRLQEQHGRDTEQYLRAMLAEGPFHPFSKHASLNEVSARFGRDVPADYPLPVAPGHVRKAKHTCRRPDCPFKGTDRACRGGRECEGRVRLGSFQRVIGSPLVFCNAGMRIAL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias292-311Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAMXCT010000355
EMBL· GenBank· DDBJ
CAI3977620.1
EMBL· GenBank· DDBJ
Genomic DNA
CAMXCT020000355
EMBL· GenBank· DDBJ
CAL1130995.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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