A0A9N8V7Z2 · A0A9N8V7Z2_9GLOM
- ProteinSqualene synthase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids448 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.
Catalytic activity
- 2 (2E,6E)-farnesyl diphosphate + NADH + H+ = squalene + 2 diphosphate + NAD+
Cofactor
Pathway
Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | farnesyl-diphosphate farnesyltransferase activity | |
Molecular Function | squalene synthase activity | |
Biological Process | ergosterol biosynthetic process | |
Biological Process | farnesyl diphosphate metabolic process |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSqualene synthase
- EC number
- Short namesSQS ; SS
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Glomeromycotina > Glomeromycetes > Archaeosporales > Ambisporaceae > Ambispora
Accessions
- Primary accessionA0A9N8V7Z2
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 300-319 | Helical | ||||
Sequence: IFNFCAIPQVMAIATLALVF | ||||||
Transmembrane | 407-430 | Helical | ||||
Sequence: LNLFDAQLFILFVLLLLATTGWAM |
Keywords
- Cellular component
Structure
Sequence
- Sequence statusComplete
- Length448
- Mass (Da)51,537
- Last updated2023-09-13 v1
- ChecksumCD1F962013659F78
Keywords
- Technical term