A0A9N8V1L3 · A0A9N8V1L3_9GLOM

  • Protein
    Autophagy-related protein 11
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular ComponentAtg1/ULK1 kinase complex
Cellular Componentphagophore assembly site membrane
Cellular Componentvacuolar membrane
Molecular Functionmolecular adaptor activity
Molecular Functionprotein kinase binding
Biological Processautophagosome assembly
Biological Processautophagy of mitochondrion
Biological Processautophagy of peroxisome
Biological Processpiecemeal microautophagy of the nucleus
Biological Processpositive regulation of autophagy of mitochondrion
Biological Processpositive regulation of protein phosphorylation
Biological Processprotein transport
Biological Processreticulophagy

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Autophagy-related protein 11

Gene names

    • ORF names
      AGERDE_LOCUS443

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • MT106
  • Taxonomic lineage
    Eukaryota > Fungi > Fungi incertae sedis > Mucoromycota > Glomeromycotina > Glomeromycetes > Archaeosporales > Ambisporaceae > Ambispora

Accessions

  • Primary accession
    A0A9N8V1L3

Proteomes

Subcellular Location

Membrane
; Peripheral membrane protein
Preautophagosomal structure membrane
; Peripheral membrane protein
Vacuole membrane
; Peripheral membrane protein
Note: During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole.

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, region, compositional bias, coiled coil.

TypeIDPosition(s)Description
Domain133-484Autophagy protein ATG17-like
Region534-554Disordered
Compositional bias589-605Polar residues
Region589-623Disordered
Coiled coil634-661
Coiled coil706-1099
Coiled coil1144-1171
Domain1290-1410Autophagy-related protein 11 C-terminal
Region1415-1452Disordered
Compositional bias1419-1433Basic and acidic residues
Compositional bias1434-1452Polar residues
Compositional bias1468-1516Polar residues
Region1468-1523Disordered
Region1539-1561Disordered

Sequence similarities

Belongs to the ATG11 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,561
  • Mass (Da)
    180,858
  • Last updated
    2023-09-13 v1
  • Checksum
    20434570E4CC120C
MKLFRAETGKRLAVRKSIDGLDTLKAELETISGIPRASQILMTSFGMELVPDMMAEATQAEGKDEYIIFLFNRELLDASVKNVDSLSENPILETPVIASAAAAARKNPTKLRRTWENVNLTEECGEYIKLFQALQAQGQSYVRSAGTHAEICERFYQEQRVQLMALGVAMTNLNSHSRSIAEAHQDFYTYAVKEISKNDQIIKSVPENFELMRRITIHPELLRLLRKDSKLTQQPPYVLINFVDVDELSALAKKGREVFEHLSKQVSDLDQNVRLVQEGTENLQKKSFNGHFPSMETQLTKVRELFESIKKFSETLERDLERVKSKVANLLNPSSSNNDTNVSSAAIKTIEAFEQLASIHARDYIPDMEKRDQNIREQVKIFTRWKNTFTVTLISSLQEISKLESSLARIPNTLSELVTQIREQDYKRLWDVHQIPLAYGMTIVEIVRRKEYTKLLLEKSHVVAEVMAHFRELEQKRRDVYRLELKKHVPFNLPALDENPPSCEISMPNIRDDQLPEFSREDIQAFLDLISQMSSPHTNQRPISQQTKSVRQSQASEDPYLALQNTLIKSFGQLEGMNADFQRIVEKRSRTPTSLSPTMQLSSVGRREKRNNRQNMSENDASFDYNNSNFDLLLMEKTKQLEGAEEKLKAYESRIKSLENLLQTNYKASKFTTLLPNPDPSQEKAFTTTQELSNLKSTHAGVLKEKDILERKTKDIEAHFREMESQYGQLTKDKGELEARYNGSVKEKETLQNRVFDLEKNQQEMAGLLEELKKEKEALSRRAIEMEQRSQNLEASLTEVCKDKQNLENIYFDTLREKDAIEKQKEELEKRCQDVSKENNTNRNTFQELESYIEELKDFESKSSSEIASLKKVIEENEKYNEEAKQTEASLREKIHSLEIDFAQTERMCDLHKEKWDEANVEKKKFEKIKNELEQQLADLQNNMQIMKEDFDQQYDKLHEGHETVKKELMDKIQNLEERYESMLLEMLDKCEEHKKECEKYEKEIENLQEALDLADQDWKKTLARNLSEYETHRDQLLAEIELLKLKAKAEKEAETQTKEELIKAQERIVQIENDLMDLKAENTDYQEALRKSDKLVKEITESILQNLPTVVSNVGSSSDSEQIMPSSLNINPIKLIRKLGIALNLLNKEFQEQRQSLEDTRRDCDGLESDMKERTTYARLLSKELWEYYSHIRTLMSDMQVAIPISLNIRPPFEKISELSDDERSKSPEPTLSDSYLAEDLNQFFNNYTYNDDNRDQENEWPKDKYELLITLAQKVDLEEVRDLLRRSPKEAESLARKYQKGYKNYKEKHIKALAESKDKIAFRNFKVGDLALFLPTRNSTAKPWAAFNISFPHYFLRSNDSINNQTKERDWIVSRITGMTEHVVDKADPTSNPFDLPNGVKFYLLDVENLENSPQQISSHHRRRTDSMRLENTRDNSQTMSMSGIKSMSSSLSNLTTTTIFEDLFSTRSPSSRSNPKRTTDYSAQQQPLRTSNTDYNNTFASSVDNNDIDNAPPTPSKRRSFIDALTPSRYLSVLSMSSPSIASPPDEETVENSIFTYQ

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias589-605Polar residues
Compositional bias1419-1433Basic and acidic residues
Compositional bias1434-1452Polar residues
Compositional bias1468-1516Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CAJVPL010000022
EMBL· GenBank· DDBJ
CAG8434949.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp