A0A9J7KU24 · A0A9J7KU24_BRAFL

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

  • Endopeptidase of broad specificity.
    EC:3.4.24.81 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site, active site.

169450100150200250300350400450500550600650
Type
IDPosition(s)Description
Binding site370Zn2+ (UniProtKB | ChEBI); catalytic
Active site371
Binding site374Zn2+ (UniProtKB | ChEBI); catalytic
Binding site380Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionmetal ion binding
Molecular Functionmetalloendopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ADAM10 endopeptidase
  • EC number

Gene names

    • Name
      LOC118412071

Organism names

Accessions

  • Primary accession
    A0A9J7KU24

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane648-673Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-20
ChainPRO_503989605621-694ADAM10 endopeptidase

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain216-435Peptidase M12B
Domain436-535Disintegrin

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    694
  • Mass (Da)
    76,618
  • Last updated
    2023-06-28 v1
  • Checksum
    F39CDCD125BDDFB2
MAEMRLLVLVSAAWWFFVQGEQLNQFVTHFEGLRYDTDRLHAKHQRARRAVLPEESRVHLAFFAHGRDFHLQMSKDNSMFSRDFQLETTGGIQQMDLSHIYSGHVVGDPKSVCHGSIIAGRFEGFVYTSDDDYYIEPAERYFNSTQDFHSVMYKAQDVIDPAPHGHKARCGVHEDHVVIEPHDQSEEDKDGTDLLHEKKKYSPPHQRHRRAPGDKNTCPIFIMADHKFFEKYRTWEATVAQIAAHVKAANLIYRPLELDGRTGYGVTVSRLKINTTEDKVYPDNPFREDFIGAEAYLDHISNMNHNDYCLAYGFTDRDFEGTLGIAWTGAICSSHLSYAGIFQSRNTGLVTVQLFGNHIPTKVSHITFAHEIGHSWGSPHDPPMCTPGGFDGNYIMFAQATSGDRPNNSKMSRCSVDRMSLTVAARAFRCFEVEQATLCGNGIVEEGEECDCGFQDVCDRIGDRCCNGATPGVIGVGCTRKQGATCSPSEGPCCNPETCSYRSASEVCTKETECALSASCSGISADCPKPANKSGSCAEGSNTCVGGECVGSICDLDNMESCQCTLKADGSNVKDLCQVCCQQPGQPGSCKPYTARTILKPVGSPCDNNKGYCDALRKCREVDIDGPLARIKRLLLTDEGTEWVKNNWWVILLGILGVIGVLVGVIFCLNAVVPSSIEQARKKARIDSLSLQPS

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

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