A0A9J7HXF1 · A0A9J7HXF1_BRAFL

Function

function

Serine/threonine kinase that plays a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site24-32ATP (UniProtKB | ChEBI)
Binding site47ATP (UniProtKB | ChEBI)
Active site138Proton acceptor

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctionMAP kinase kinase kinase kinase activity
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mitogen-activated protein kinase kinase kinase kinase
  • EC number

Gene names

    • Name
      LOC118408897

Organism names

Accessions

  • Primary accession
    A0A9J7HXF1

Proteomes

Family & Domains

Features

Showing features for domain, region, compositional bias.

Type
IDPosition(s)Description
Domain18-275Protein kinase
Region292-366Disordered
Compositional bias311-366Basic and acidic residues
Region394-524Disordered
Compositional bias407-424Polar residues
Compositional bias481-500Acidic residues
Compositional bias501-516Pro residues
Domain566-887CNH

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    914
  • Mass (Da)
    103,047
  • Last updated
    2023-06-28 v1
  • Checksum
    C12A9E9DD6E37CFE
MGTPRTATIMRRNPQEDFELIQRIGSGTYGDVYKARNMQTDELAAIKVIKLEPGDDFAIIQQEIIMMKECKHINIVAYFGSYLRRDKLWICMEFCGGGSMQDIYHITGPLKETQIAYVCRETLQGLAYLHSRGKMHRDIKGANILLTDEGNVKLADFGVSAQITATMAKRKSFIGTPYWMAPEVAAVERKGGYNQQCDVWAVGITAIEFAELQPPMFDLHPMRVLFLMSKSGFVPPKLKDKNKWTPNFHNFVKLALTKNPKKRPTAEKMIQHPFFQQPLSHRLGKDLLEMASNPSSYQNHDDEDEEDRGEPTLEVPQRISSRKKEDRKERTKSEIDMENVNFEPPLRRETEPQQDEVRAGEVPNRVRRNDDEFAGAWRPVLEIDGSKSLIKSVEEELHRRGHTTTLEYSDAAGTDQSSSLPANGTGRPPGAPKAGQKSASDSEIISTQERRDGGTPPAHTTPPALPPKERANGVVPTANGEDMEEEQDVSEQENSEPPPDDEPPPPEVPPKVGDMNRPRPPMRSTWSRICHQETLAILQEPQCNGLPPTPKVHMGACFSKVFNGCPLKVNCAVSWVHPQTRDQHIIVGCNEGIYTLNLTQLHEATMDHLFPRRCTWMYVINNILLSVSEGKTPHVYSHNLVGLHDRTHTLGFNIPTHKLPDRIVPRKYAISTKLPDTKGCLRCCVVRNPYNGHKYLCTAVPNGVVLYQWYEPMQKFMLVKLPPYVPQHCEFSIPQPLRVFEMLVTPIAEYPLVCIGVSKGTNQNLLHFDTVNLNLSSSWFTEQGSALFDGENQLDVVNVTQLEKDTVLVAFDREVKIVNLSGKLKSSKKLAAELHFDFYTESIVCLQDSVLAFHKHGMQGRSFKANEVTQEICDKSRIFRLIGSDRMIVLESRPSDDPTAPSNLYILAGHEATY

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias311-366Basic and acidic residues
Compositional bias407-424Polar residues
Compositional bias481-500Acidic residues
Compositional bias501-516Pro residues

Keywords

Sequence databases

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp