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A0A9J6QUS1 · A0A9J6QUS1_9FIRM

  • Protein
    Protein translocase subunit SecA
  • Gene
    secA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP + H2O + cellular proteinSide 1 = ADP + phosphate + cellular proteinSide 2.
    EC:7.4.2.8 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site.

167950100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site17ATP (UniProtKB | ChEBI)
Binding site35-39ATP (UniProtKB | ChEBI)
Binding site423ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcell envelope Sec protein transport complex
Cellular Componentcytosol
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular Functionhelicase activity
Biological Processintracellular protein transmembrane transport
Biological Processprotein import
Biological Processprotein targeting
Biological Processprotein transport by the Sec complex

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein translocase subunit SecA
  • EC number

Gene names

    • Name
      secA
    • ORF names
      OBO34_10480

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • ASD5510
  • Taxonomic lineage
    Bacteria > Bacillota > Clostridia > Eubacteriales > Eubacteriales Family XIII. Incertae Sedis > Hominibacterium

Accessions

  • Primary accession
    A0A9J6QUS1

Proteomes

Subcellular Location

Cell membrane
; Peripheral membrane protein
Cytoplasm
Membrane
; Peripheral membrane protein
Note: Distribution is 50-50.

Keywords

Interaction

Subunit

Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-503SecA family profile
Domain19-242Helicase ATP-binding
Domain345-512Helicase C-terminal

Sequence similarities

Belongs to the SecA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    679
  • Mass (Da)
    77,717
  • Last updated
    2023-06-28 v1
  • MD5 Checksum
    E17D7C291BA96F662663D7EA326F0728
MKETIIRCKGMVLFDTQLSAAYAMEQGMIAELPTGEGKTLAAVVTALSLALSGEQVQILVFNDYLAARDYKENKEVFQFCGLSCGCILQTTKREHRQAAYDCNILYITAREAGFDYLRNFMAFRESGLLRQHFHTAIVDEADSILIDEAGIPLVLAGEEPTIDKNYMTVWKTVEELDAQDIEFQEKEHQVWLTERGAVHAERLLGVNNLYELENAHYLEMIHTFLEARLLYKKDRDYIVKNGTVFVIEHTTGRVAEGRRFPDHLHLAIEIKEGVKARKGSQIYNMMPLQFYLLKYRRLCGMTGTAWSSRKELKNMYDLSVIRIPPHVPCIRRDHEDVILSTNQALYTQVYHKIRQIHQTGQPILIGTQSVEESEALAGALRKRNLPCFVLNAKEDEKEAELIALAGRPYRITISTNMAGRGVDIKLDKDAATAGGLFVLSTGINRSFRIDQQLRGRTGRQGEPGESQFFISMEQPLIKRHVIENTGKVQIRRIQRMAEGEDAQMRYLLEKYSLILEKHRRMITQYREVVLRDIKSVHFFETNAPVLYKKRVAESGTQGVLCAEQQLLLFYINQHWVDYLAAMESARESIHFAILGGEEPVDVYQRFAVRAFAEMEEDIKKDVLSKLKTCKITEHGVDLRGEGLIKATNTWTYMIDESKSQFAKVPSLLKYIRKLKGTQL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAOSHN010000004
EMBL· GenBank· DDBJ
MCU7378779.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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