A0A9J6GBP2 · A0A9J6GBP2_HAELO
- ProteinDNA repair and recombination protein RAD54-like
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1156 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
function
Involved in mitotic DNA repair and meiotic recombination. Functions in the recombinational DNA repair pathway. Essential for interhomolog gene conversion (GC), but may have a less important role in intersister GC than spn-A/Rad51. In the presence of DNA, spn-A/Rad51 enhances the ATPase activity of okr/Rad54.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | ATP-dependent chromatin remodeler activity | |
Molecular Function | DNA binding | |
Molecular Function | helicase activity | |
Molecular Function | hydrolase activity | |
Biological Process | cell division | |
Biological Process | meiotic cell cycle | |
Biological Process | transcription-coupled nucleotide-excision repair |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameDNA repair and recombination protein RAD54-like
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Parasitiformes > Ixodida > Ixodoidea > Ixodidae > Haemaphysalinae > Haemaphysalis
Accessions
- Primary accessionA0A9J6GBP2
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Interacts (via N-terminus) with spn-A/Rad51.
Structure
Family & Domains
Features
Showing features for domain, region, coiled coil, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 50-143 | THAP-type | ||||
Sequence: VPACRASVLFDLSSNAGLLCTRLLIELPTEATGSVISRSASLREKWLHAILRDTFPSTAIRDRSVVCSLHFRPTDFKKDFTRRLLKPGAVPSVF | ||||||
Region | 201-249 | Disordered | ||||
Sequence: LESTTQGTARKRKRTPSGVSLARGQLGGTNDGPAKSPRLNHEHSDDDSN | ||||||
Coiled coil | 308-342 | |||||
Sequence: CKRWRERERALKTKNERLRRTVDSYKEELLKLKEA | ||||||
Domain | 820-965 | Helicase C-terminal | ||||
Sequence: VVESLLKLWHAQGHRALLFTQSRQMLLILERFVKEQGYSYMLMTGSTPIGSRQPAINKFNQDSSVFVFLLTTRVGGLGVNLTGADRVVDLRPDWNPSTDMQARERAWRIRPEAGRHRLYRLLTAGTIEEKIYTDLQAVPDQPSAQG | ||||||
Region | 985-1030 | Disordered | ||||
Sequence: RPGAEAHRDERHFLGTGSTLRRPKKKSKGPKGAAQGDASTALAPDK | ||||||
Compositional bias | 987-1001 | Basic and acidic residues | ||||
Sequence: GAEAHRDERHFLGTG | ||||||
Region | 1047-1071 | Disordered | ||||
Sequence: SAKKAGANGKEAEKVGKKEGKKHRR |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,156
- Mass (Da)128,229
- Last updated2023-06-28 v1
- ChecksumCEAFDFC486CE047D
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 987-1001 | Basic and acidic residues | ||||
Sequence: GAEAHRDERHFLGTG |
Keywords
- Technical term