A0A9E7W0S6 · A0A9E7W0S6_9MICO

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

1971100200300400500600700800900
TypeIDPosition(s)Description
Binding site745ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionaminoacyl-tRNA editing activity
Molecular FunctionATP binding
Molecular Functionleucine-tRNA ligase activity
Biological Processleucyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Leucine--tRNA ligase
  • EC number
  • Alternative names
    • Leucyl-tRNA synthetase
      (LeuRS
      )

Gene names

    • Name
      leuS
    • ORF names
      LJ362_09415

Organism names

  • Taxonomic identifier
  • Strain
    • JSBI002
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Brevibacteriaceae > Brevibacterium

Accessions

  • Primary accession
    A0A9E7W0S6

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region, compositional bias, domain, motif.

TypeIDPosition(s)Description
Region23-60Disordered
Compositional bias29-47Polar residues
Domain71-176Methionyl/Leucyl tRNA synthetase
Domain310-509Leucyl-tRNA synthetase editing
Motif742-746'KMSKS' region
Domain818-933Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    971
  • Mass (Da)
    108,164
  • Last updated
    2023-05-03 v1
  • Checksum
    0D1CCBFD0246D595
MTTNPEETGFRYDAALAEKIEKSWQRTWEESGTFHTPNPTGDLGELDSQDASSPYGPPADLSERESLYIMDMFPYPSGVGLHVGHPLGYLGTDVYGRYQRMRGHNVMHALSYDAFGLPADLYAVQTGQHPRITTDANIANMTEQLRRLGLAHDVRRRFATTDDEFVRWTQWIFLQIFNSWYDTEATTPDGEAKGAARPIDTLIEQFASGARPTPDGRAWSELSPAERENVLQGYRLAYVSESPVNWCPGLGTVLANEEVTAEGLSERGNYPVFTRRLRQWNMRITAYADRLIDDLDVLDWPHAIHAMQVNWIGRSKGALLRLPIAGDDASDIEVYTTRPDTLFGATYLVLSPEHPQVADLTAESWDETTPESWRGGEATPAGAIAAYQRAAAAKTDADRQQSREKTGIFTGSYALNPATGAQVPIFIADYVLMGYGTGAIMAVPAEDARDWDFAKAFGLPYIRTVQPPADHDEDAPFTGTGVMINSANAEIDINGLEIDAAKARVTEWLAGKGLATESTQYRLRDWLFSRQRYWGEPFPIVYDENGTPIALPDEMLPVQLPEVDDFAPRTYAPDDADSRPEPALSRNQEWTSIELDLGDGPKTYQRETNTMPNWAGSSWYQLRYADPHNDDRLVDPANEKYWLGPRASKPRGGADLYVGGQEHAVLHLLYARFWHKILFDLGHISSSEPFHRLVNQGYIQAYAYTDSRGVYVPAAEVEERTESNGELTFWYDGEQVNREYGKIGKSLKNSVMPDEMYDAFGADTFRVYEMSMGPLEQDRPWDTRAVVGAQRFLQRVWRLFVDETTGGSVVADGEADAESLKVLHQVIDGVREDMDHLRFNTAISKLIVLTNHATKQGGATRDVLEPLTIMLAPFAPHLAEELWSRLGHESTVTYAAFPEADPKHLVAETVTCVVQVKGKVRARLEVAPDIPAEELEKLALESPNAVKALGGAGVRKVIVRAPKLVNIVPDA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias29-47Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP110341
EMBL· GenBank· DDBJ
UZD60926.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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