A0A9E7W0D8 · A0A9E7W0D8_9MICO

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site26-29ATP (UniProtKB | ChEBI)
Binding site66UMP (UniProtKB | ChEBI)
Binding site67ATP (UniProtKB | ChEBI)
Binding site71ATP (UniProtKB | ChEBI)
Binding site86UMP (UniProtKB | ChEBI)
Binding site147-154UMP (UniProtKB | ChEBI)
Binding site175ATP (UniProtKB | ChEBI)
Binding site181ATP (UniProtKB | ChEBI)
Binding site184ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      LJ362_11145

Organism names

  • Taxonomic identifier
  • Strain
    • JSBI002
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Micrococcales > Brevibacteriaceae > Brevibacterium

Accessions

  • Primary accession
    A0A9E7W0D8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain22-228Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    250
  • Mass (Da)
    27,054
  • Last updated
    2023-05-03 v1
  • MD5 Checksum
    1B34BFAD5E11121F5B71FA19A2CAEFAD
MTSTPVHESSYASRAVRTHRRRVLLKLSGEVFGGGKIGVDPDVVAAVAREVAPTTEDVEVSIVVGGGNFFRGAELSQRGMDRTRADYMGMLGTVMNCLALQDFLEQTGVDTRVQTAIPMSQVAESYIPRRAMRHMEKNRVVIFGAGAGLPYFSTDTVAAQRALEVHADEVLIAKNGVDGVYTADPKVDPNAEKISEISYQDALQRGLKVVDATAFSLCMDNKLPMHVFGMEGEGNLRKAIIGEKIGTVVH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP110341
EMBL· GenBank· DDBJ
UZD61242.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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