A0A9E7MP28 · A0A9E7MP28_9CAUD
- ProteinNAD--protein ADP-ribosyltransferase modA
- GenemodA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids200 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
ADP-ribosyltransferase that efficiently ADP-ribosylates both alpha subunits of host RNA polymerase RPOA. The ModA-induced ADP-ribosylation of RPOA alpha subunits inhibits transcription from viral early promoters.
Catalytic activity
- L-arginyl-[protein] + NAD+ = H+ + N(omega)-(ADP-D-ribosyl)-L-arginyl-[protein] + nicotinamide
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | virion component | |
Molecular Function | NAD+-protein-arginine ADP-ribosyltransferase activity | |
Molecular Function | nucleotidyltransferase activity |
Keywords
- Molecular function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNAD--protein ADP-ribosyltransferase modA
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageViruses > Duplodnaviria > Heunggongvirae > Uroviricota > Caudoviricetes > Straboviridae > Tevenvirinae > Tequatrovirus
Accessions
- Primary accessionA0A9E7MP28
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Note: This protein is injected from the virion into the bacterial cell.
Keywords
- Cellular component
Structure
Family & Domains
Sequence similarities
Belongs to the Tevenvirinae NAD--protein ADP-ribosyltransferase modA family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length200
- Mass (Da)23,452
- Last updated2023-05-03 v1
- ChecksumB8F0E2E7615B1C81