A0A9D4YHL6 · A0A9D4YHL6_PEA

Function

function

Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular ComponentMCM complex
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionhydrolase activity
Molecular FunctionRNA binding
Molecular Functionsingle-stranded DNA binding
Molecular Functionsingle-stranded DNA helicase activity
Biological ProcessDNA replication initiation
Biological ProcessDNA strand elongation involved in DNA replication
Biological ProcessDNA unwinding involved in DNA replication
Biological Processdouble-strand break repair via break-induced replication

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA replication licensing factor MCM7
  • EC number

Gene names

    • Name
      MCM7
    • ORF names
      KIW84_024884

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Zhongwan 6
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > Hologalegina > IRL clade > Fabeae > Pisum

Accessions

  • Primary accession
    A0A9D4YHL6

Proteomes

Subcellular Location

Keywords

  • Cellular component

Family & Domains

Features

Showing features for region, compositional bias, domain.

TypeIDPosition(s)Description
Region19-39Disordered
Compositional bias23-37Basic residues
Region92-125Disordered
Compositional bias105-123Basic and acidic residues
Domain183-229RRM
Domain404-444MCM

Sequence similarities

Belongs to the MCM family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    458
  • Mass (Da)
    52,126
  • Last updated
    2023-05-03 v1
  • Checksum
    4E1A4B1EE1F69106
MLTLKETVQCNDQWYLDSRPRRKYKNSRPKVRVGLPKKNPKVLKPAFTIPPKLLQSLAEDPKWDEKGSVTQNYNSFGVVNDPNSLTDNLQAPSVSDDPNDSGSDLEEDDLKSALGKRRRDGKSALPQPLTSIQRLYISRLVEKYGADFQRMMMDIKLNPMQHSVATLEKLCMSYYIYKNKNPLIIFVGGLNPNVTDEDLRQTFSEYGEITSVKIPVGKGCGFVQFANSKIITVKNYYVITRCSDVKPLMQVAVYTCEDCGFEIYQEVTTRIFMPLFECPSRRCVMNKSKGNVILQLRASKFLRFQEAKIQELAEHVPKGHIPRTMIVHLRGELTRKVAPGDVVELSGIFLPIPYVGFRAMRAGLVADTYLEAMSVSHFKKKYEEYELRGDEEEQIKRLAEDGDIYDKLARSLAPEIFGHEDIKKALLLLLVGAPHRQLKDGMKVINFILFEAHMFNGA

Computationally mapped potential isoform sequences

There are 7 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A9D4YGP7A0A9D4YGP7_PEAKIW84_024884146
A0A9D5AXZ8A0A9D5AXZ8_PEAMCM7442
A0A9D5B3R2A0A9D5B3R2_PEAKIW84_033419109
A0A9D4Y041A0A9D4Y041_PEAKIW84_033419108
A0A9D4YIZ9A0A9D4YIZ9_PEAKIW84_024884130
A0A9D4YLA5A0A9D4YLA5_PEAMCM7449
A0A9D4YML9A0A9D4YML9_PEAKIW84_024884167

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias23-37Basic residues
Compositional bias105-123Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAMSHJ010000002
EMBL· GenBank· DDBJ
KAI5439274.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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