A0A9D1YTF4 · A0A9D1YTF4_9MICO

Function

function

Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.

Miscellaneous

The reaction proceeds by a bi uni uni bi ping pong mechanism.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site35-42ATP (UniProtKB | ChEBI)
Active site42Proton donor
Binding site66(R)-pantoate (UniProtKB | ChEBI)
Binding site66beta-alanine (UniProtKB | ChEBI)
Binding site153-156ATP (UniProtKB | ChEBI)
Binding site159(R)-pantoate (UniProtKB | ChEBI)
Binding site190-193ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular Functionpantoate-beta-alanine ligase activity
Biological Processpantothenate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Pantothenate synthetase
  • EC number
  • Short names
    PS
  • Alternative names
    • Pantoate--beta-alanine ligase
    • Pantoate-activating enzyme

Gene names

    • Name
      panC
    • ORF names
      H9830_01940

Organism names

  • Taxonomic identifier
  • Strain
    • ChiGjej1B1-98
  • Taxonomic lineage
    Bacteria > Bacillati > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Agrococcus

Accessions

  • Primary accession
    A0A9D1YTF4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the pantothenate synthetase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    30,739
  • Last updated
    2023-05-03 v1
  • MD5 Checksum
    5D0C295C01E8CDF8B71A9CD9316BB04C
MPAVPTSTIRSIEALRQALATERASGRSIALVPTMGALHAGHLALVAAAREQADVVVVSIFVNPTQFGDKLDLEAYPRTLDHDLEKLDAYEVGYVFAPSTEEIYPNGKTEITVQAGMTASRFEGRSRPGHFDGVLTVVSKLLNIVEPDFACFGEKDAQQLHLVRRLVADLDFATEIVPVATERDSDGLALSSRNARIDPARREHALAIPRALVAASRSADLGVEPMLAAAQGVMQSDTKVKLDYLAAVDPDTFLPVDENHSGAVRVLIAGTVDGVRLIDNTLVRIP

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DXDC01000052
EMBL· GenBank· DDBJ
HIY65023.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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