A0A9D1RI95 · A0A9D1RI95_9BACT
- ProteinAminopeptidase N
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids771 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 304 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 305 | Proton acceptor | |||
Binding site | 308 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Binding site | 327 | Zn2+ (UniProtKB | ChEBI); catalytic | |||
Active site | 385 | Proton donor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | metallopeptidase activity | |
Molecular Function | zinc ion binding | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAminopeptidase N
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Bacteroidia > Bacteroidales > Candidatus Onthomorpha
Accessions
- Primary accessionA0A9D1RI95
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-22 | ||||
Chain | PRO_5038758457 | 23-771 | Aminopeptidase N | ||
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 73-206 | Aminopeptidase N-like N-terminal | |||
Domain | 296-443 | Peptidase M1 membrane alanine aminopeptidase | |||
Domain | 695-767 | Secretion system C-terminal sorting | |||
Sequence similarities
Belongs to the peptidase M1 family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length771
- Mass (Da)88,198
- Last updated2023-05-03 v1
- Checksum2DAA0B3349A95A19
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DXGG01000071 EMBL· GenBank· DDBJ | HIW87071.1 EMBL· GenBank· DDBJ | Genomic DNA |