A0A9C7BH69 · A0A9C7BH69_9THEO
- ProteinHomoserine O-acetyltransferase
- GenemetX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids367 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
Catalytic activity
- L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; O-acetyl-L-homoserine from L-homoserine: step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Active site | 162 | Nucleophile | ||||
Sequence: S | ||||||
Binding site | 218 | substrate | ||||
Sequence: R | ||||||
Active site | 313 | |||||
Sequence: D | ||||||
Active site | 346 | |||||
Sequence: H | ||||||
Binding site | 347 | substrate | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | homoserine O-acetyltransferase activity | |
Biological Process | homoserine metabolic process | |
Biological Process | methionine biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomoserine O-acetyltransferase
- EC number
- Short namesHAT
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Thermoanaerobacterales > Thermoanaerobacteraceae > Gelria
Accessions
- Primary accessionA0A9C7BH69
Proteomes
Subcellular Location
Interaction
Subunit
Homodimer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 56-351 | AB hydrolase-1 | ||||
Sequence: NAILICHALTGDAHAAGRHTPEDKAPGWWDPLIGPGRAFDTERYYVICSNILGGCAGSTGPTSLHPATGRPYGRSFPVITVADMVKLQHRLLAELGVRRLVAVAGGSLGGLQALEWGRAYPALVENVVAIGAAAALSTQALAWNYAQRQAILLDPVQGLALARAIGTITYKSDLSWRRKFGHAWASPPEERYRLDSRLQVESYLAYQGEKLVRRFDADSYLYLTKAMDLFDLQEGYPSLTAALAGYRPRVLMVGISSDFLFPPYQQKEIVRALRANKKSAAYREIISPYGHDAFLI |
Sequence similarities
Belongs to the AB hydrolase superfamily. MetX family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length367
- Mass (Da)40,038
- Last updated2023-05-03 v1
- Checksum08869395B67EFDF8
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AP024619 EMBL· GenBank· DDBJ | BCV24356.1 EMBL· GenBank· DDBJ | Genomic DNA |