A0A994J7X8 · A0A994J7X8_HUMAN

  • Protein
    Calcium/calmodulin-dependent protein kinase type II subunit delta
  • Gene
    CAMK2D
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site43ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentsarcolemma
Cellular Componentsarcoplasmic reticulum membrane
Molecular FunctionATP binding
Molecular Functioncalcium/calmodulin-dependent protein kinase activity
Molecular Functioncalmodulin binding
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Calcium/calmodulin-dependent protein kinase type II subunit delta
  • EC number

Gene names

    • Name
      CAMK2D

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A994J7X8

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane, sarcolemma
; Peripheral membrane protein
Sarcoplasmic reticulum membrane
; Peripheral membrane protein

Keywords

Disease & Variants

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 311 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Genetic variation databases

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)235PRIDEPhosphoserine
Modified residue (large scale data)276PRIDEPhosphoserine
Modified residue (large scale data)277PRIDEPhosphothreonine
Modified residue (large scale data)280PRIDEPhosphoserine
Modified residue (large scale data)287PRIDEPhosphothreonine
Modified residue (large scale data)306PRIDEPhosphothreonine
Modified residue (large scale data)307PRIDEPhosphothreonine
Modified residue (large scale data)311PRIDEPhosphothreonine
Modified residue (large scale data)315PRIDEPhosphoserine
Modified residue (large scale data)319PRIDEPhosphoserine
Modified residue (large scale data)364PRIDEPhosphothreonine
Modified residue (large scale data)375PRIDEPhosphoserine
Modified residue (large scale data)376PRIDEPhosphothreonine
Modified residue (large scale data)378PRIDEPhosphoserine
Modified residue (large scale data)379PRIDEPhosphoserine
Modified residue (large scale data)381PRIDEPhosphothreonine
Modified residue (large scale data)382PRIDEPhosphothreonine
Modified residue (large scale data)517PRIDEPhosphoserine

Proteomic databases

Structure

3D structure databases

Family & Domains

Features

Showing features for domain, compositional bias, region.

TypeIDPosition(s)Description
Domain14-272Protein kinase
Compositional bias348-378Polar residues
Region348-386Disordered

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    523
  • Mass (Da)
    58,998
  • Last updated
    2023-05-03 v1
  • Checksum
    59FD5E07C9A62DDF
MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKLKGAILTTMLATRNFSAAKSLLKKPDGVKKRKSSSSVQMMINNKANVVTSPKENIPTPALEPQTTVIHNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIN

Computationally mapped potential isoform sequences

There are 22 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
Q13557KCC2D_HUMANCAMK2D499
E9PBG7E9PBG7_HUMANCAMK2D512
H0Y9J2H0Y9J2_HUMANCAMK2D182
D6R938D6R938_HUMANCAMK2D498
H0Y9C2H0Y9C2_HUMANCAMK2D194
A0A8V8TPJ8A0A8V8TPJ8_HUMANCAMK2D512
A0A8V8TPK3A0A8V8TPK3_HUMANCAMK2D491
A0A8V8TPM4A0A8V8TPM4_HUMANCAMK2D347
A0A8V8TQ10A0A8V8TQ10_HUMANCAMK2D71
A0A8V8TPY4A0A8V8TPY4_HUMANCAMK2D491
E9PF82E9PF82_HUMANCAMK2D533
A0A8V8TN60A0A8V8TN60_HUMANCAMK2D491
A0A8V8TN65A0A8V8TN65_HUMANCAMK2D512
A0A8V8TN88A0A8V8TN88_HUMANCAMK2D477
A0A8V8TNA1A0A8V8TNA1_HUMANCAMK2D511
A0A8V8TNA7A0A8V8TNA7_HUMANCAMK2D492
A0A8V8TND4A0A8V8TND4_HUMANCAMK2D523
A0A8V8TNN4A0A8V8TNN4_HUMANCAMK2D119
A0A8V8TNN9A0A8V8TNN9_HUMANCAMK2D344
A0A8V8TNR6A0A8V8TNR6_HUMANCAMK2D255
A0A994J5B0A0A994J5B0_HUMANCAMK2D503
A0A994J516A0A994J516_HUMANCAMK2D503

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias348-378Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC004056
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC004168
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC093900
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC107386
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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