A0A994J6K1 · A0A994J6K1_HUMAN

  • Protein
    Glutamate ionotropic receptor AMPA type subunit 2
  • Gene
    GRIA2
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    1/5

Function

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Molecular Functionligand-gated monoatomic ion channel activity

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Glutamate ionotropic receptor AMPA type subunit 2

Gene names

    • Name
      GRIA2

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo

Accessions

  • Primary accession
    A0A994J6K1

Proteomes

Organism-specific databases

Subcellular Location

Postsynaptic cell membrane
; Multi-pass membrane protein
Postsynaptic density

Keywords

  • Cellular component

Disease & Variants

Genetic variation databases

PTM/Processing

Keywords

Proteomic databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain362-427Ionotropic glutamate receptor L-glutamate and glycine-binding

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    428
  • Mass (Da)
    48,215
  • Last updated
    2023-05-03 v1
  • MD5 Checksum
    B3E2DB98F95317470911FBA0F0FD878D
XLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYG

Computationally mapped potential isoform sequences

There are 25 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P42262GRIA2_HUMANGRIA2883
D6RFM6D6RFM6_HUMANGRIA257
D6RDX5D6RDX5_HUMANGRIA2124
F8W7L6F8W7L6_HUMANGRIA2730
D6RBV7D6RBV7_HUMANGRIA248
D6R9Z0D6R9Z0_HUMANGRIA2145
H0Y972H0Y972_HUMANGRIA2214
A0A994J6Z1A0A994J6Z1_HUMANGRIA2573
A0A994J6Z5A0A994J6Z5_HUMANGRIA2476
A0A994J6Z8A0A994J6Z8_HUMANGRIA2528
A0A994J6J5A0A994J6J5_HUMANGRIA2580
A0A994J6J8A0A994J6J8_HUMANGRIA2808
A0A994J6Y1A0A994J6Y1_HUMANGRIA2739
A0A994J6Y8A0A994J6Y8_HUMANGRIA2813
A0A994J4F1A0A994J4F1_HUMANGRIA2836
A0A994J4G8A0A994J4G8_HUMANGRIA2892
A0A994J4H3A0A994J4H3_HUMANGRIA2756
A0A994J3U8A0A994J3U8_HUMANGRIA2854
A0A994J3V2A0A994J3V2_HUMANGRIA2244
A0A994J3V5A0A994J3V5_HUMANGRIA2403
A0A994J404A0A994J404_HUMANGRIA2803
A0A994J413A0A994J413_HUMANGRIA2468
A0A994J422A0A994J422_HUMANGRIA2229
A0A994J425A0A994J425_HUMANGRIA2562
A0A994J418A0A994J418_HUMANGRIA2491

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC079233
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
AC112240
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Genome annotation databases

Similar Proteins

Disclaimer

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