Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling.Xie M., Kaiser M., Gershtein Y., Schnyder D., Deviatiiarov R., Gazizova G., Shagimardanova E., Zikmund T., Kerckhofs G.[...], Chagin A.S.View abstractSourceMGI: 1921620PubMedEurope PMCNat Commun 15:2367-2367 (2024)Mapped to16
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 1921620PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Reprogramming tumor-associated macrophages to outcompete endovascular endothelial progenitor cells and suppress tumor neoangiogenesis.Do M.H., Shi W., Ji L., Ladewig E., Zhang X., Srivastava R.M., Capistrano K.J., Edwards C., Malik I.[...], Li M.O.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCImmunity 56:2555-2569.e5 (2023)Mapped to19
Dietary fructose-mediated adipocyte metabolism drives antitumor CD8pisup>+pi/sup> T cell responses.Zhang Y., Yu X., Bao R., Huang H., Gu C., Lv Q., Han Q., Du X., Zhao X.Y.[...], Zou Q.View abstractSourceMGI: 1921620PubMedEurope PMCCell Metab 35:2107-2118.e6 (2023)Mapped to22
mTORC1-selective activation of translation elongation promotes disease progression in chronic lymphocytic leukemia.Malik N., Hay J., Almuhanna H.N.B., Dunn K.M., Lees J., Cassels J., Li J., Nakagawa R., Sansom O.J., Michie A.M.View abstractCategoriesPTM / ProcessingSourceMGI: 1921620PubMedEurope PMCLeukemia 37:2414-2425 (2023)Mapped to17
Steroidogenic factor 1 (SF-1; <i>Nr5a1</i>) regulates the formation of the ovarian reserve.Hughes C.H.K., Smith O.E., Meinsohn M.C., Brunelle M., Gevry N., Murphy B.D.View abstractSourceMGI: 1921620PubMedEurope PMCProc Natl Acad Sci U S A 120:e2220849120-e2220849120 (2023)Mapped to99+
Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production.Riahi Y., Kogot-Levin A., Kadosh L., Agranovich B., Malka A., Assa M., Piran R., Avrahami D., Glaser B.[...], Leibowitz G.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCDiabetologia 66:1925-1942 (2023)Mapped to21
Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis.Huang H., Jing B., Zhu F., Jiang W., Tang P., Shi L., Chen H., Ren G., Xia S.[...], Xiao B.View abstractSourceMGI: 1921620PubMedEurope PMCCell Rep 42:112801-112801 (2023)Mapped to32
Reprogramming tumour-associated macrophages to outcompete cancer cells.Zhang X., Li S., Malik I., Do M.H., Ji L., Chou C., Shi W., Capistrano K.J., Zhang J.[...], Li M.O.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCNature 619:616-623 (2023)Mapped to65
Uptake of tumor-derived microparticles induces metabolic reprogramming of macrophages in the early metastatic lung.Kersten K., You R., Liang S., Tharp K.M., Pollack J., Weaver V.M., Krummel M.F., Headley M.B.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCCell Rep 42:112582-112582 (2023)Mapped to21
Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic beta cells.Xu W., Qadir M.M.F., Nasteska D., Mota de Sa P., Gorvin C.M., Blandino-Rosano M., Evans C.R., Ho T., Potapenko E.[...], Mauvais-Jarvis F.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCCell Rep 42:112529-112529 (2023)Mapped to23
Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP.Wiebe S., Huang Z., Ladak R.J., Skalecka A., Cagnetta R., Lacaille J.C., Aguilar-Valles A., Sonenberg N.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCMol Brain 16:9-9 (2023)Mapped to25
Mechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons.Tran Nguyen Truc L., Matsuda S., Takenouchi A., Tran Thuy Huong Q., Kotani Y., Miyazaki T., Kanda H., Yoshizawa K., Tsukaguchi H.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCSci Rep 13:508-508 (2023)Mapped to40
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses.Honore E., Lacaille J.C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1921620PubMedEurope PMCMol Brain 15:101-101 (2022)Mapped to14
mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity.Zhang K., Yao E., Chuang E., Chen B., Chuang E.Y., Chuang P.T.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCNat Commun 13:7252-7252 (2022)Mapped to99+
Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss.Tariq K., Cullen E., Getz S.A., Conching A.K.S., Goyette A.R., Prina M.L., Wang W., Li M., Weston M.C., Luikart B.W.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCCell Rep 41:111574-111574 (2022)Mapped to22
SZT2 maintains hematopoietic stem cell homeostasis via nutrient-mediated mTORC1 regulation.Yin N., Jin G., Ma Y., Zhao H., Zhang G., Li M.O., Peng M.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1921620PubMedEurope PMCJ Clin Invest 132:e146272-e146272 (2022)Mapped to27
Mast cell regranulation requires a metabolic switch involving mTORC1 and a glucose-6-phosphate transporter.Iskarpatyoti J.A., Shi J., Abraham M.A., Rathore A.P.S., Miao Y., Abraham S.N.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCCell Rep 40:111346-111346 (2022)Mapped to14
Raptor downregulation rescues neuronal phenotypes in mouse models of Tuberous Sclerosis Complex.Karalis V., Caval-Holme F., Bateup H.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1921620PubMedEurope PMCNat Commun 13:4665-4665 (2022)Mapped to23
Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2.Kosillo P., Ahmed K.M., Aisenberg E.E., Karalis V., Roberts B.M., Cragg S.J., Bateup H.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1921620PubMedEurope PMCElife 11:e75398-e75398 (2022)Mapped to23
<i>Salmonella</i> Promotes Its Own Survival in B Cells by Inhibiting Autophagy.Luis L.B., Ana G.T., Carlos G.E., Abraham G.G., Iris E.G., Martha M.L., Vianney O.N.View abstractCategoriesFunctionSourceMGI: 1921620PubMedEurope PMCCells 11:2061-2061 (2022)Mapped to17
mTORC1 signaling in antigen-presenting cells of the skin restrains CD8pisup>+pi/sup> T cell priming.Pelgrom L.R., Patente T.A., Otto F., Nouwen L.V., Ozir-Fazalalikhan A., van der Ham A.J., van der Zande H.J.P., Heieis G.A., Arens R., Everts B.View abstractSourceMGI: 1921620PubMedEurope PMCCell Rep 40:111032-111032 (2022)Mapped to12