A0A977TPW1 · A0A977TPW1_9ACAR

  • Protein
    NADH-ubiquinone oxidoreductase chain 5
  • Gene
    ND5
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrial respiratory chain complex I
Molecular FunctionNADH dehydrogenase (ubiquinone) activity
Molecular FunctionNADH dehydrogenase activity
Biological ProcessATP synthesis coupled electron transport
Biological Processelectron transport coupled proton transport

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADH-ubiquinone oxidoreductase chain 5
  • EC number

Gene names

    • Name
      ND5

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Chelicerata > Arachnida > Acari > Parasitiformes > Ixodida > Ixodoidea > Ixodidae > Amblyomminae > Amblyomma

Accessions

  • Primary accession
    A0A977TPW1

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-26Helical
Transmembrane46-71Helical
Transmembrane83-102Helical
Transmembrane108-128Helical
Transmembrane140-159Helical
Transmembrane165-184Helical
Transmembrane233-255Helical
Transmembrane262-280Helical
Transmembrane286-308Helical
Transmembrane329-347Helical
Transmembrane367-388Helical
Transmembrane408-427Helical
Transmembrane447-463Helical
Transmembrane472-489Helical
Transmembrane531-546Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain39-85NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal
Domain104-379NADH:quinone oxidoreductase/Mrp antiporter membrane subunit

Sequence similarities

Belongs to the complex I subunit 5 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    547
  • Mass (Da)
    63,948
  • Last updated
    2023-02-22 v1
  • Checksum
    793687BFF1C63FE8
MFIYWSMILLLFSILFMMMFMINFNNSNLLILEYYLICIQNLDFKIYFLMDWMSTMFSSIVLFISSMVIFFSNSYMKNDVNKYSFCLIVILFVLSMVFLILMPNMFMLILGWDGLGLVSYCLVIYYQSVNSFNSGMMTIISNRVGDVMIIMSLIFMMSLGTFDLISLDLIALICGIMVVIAGMTKSAQIPFSAWLPAAMAAPTPVSSLVHSSTLVTAGVYLLMRFNFLFKINFFSTFLLKISLITLLMAGINAFFESDFKKIIAFSTLSQLSLMMISMSLGLSQLAFFHLIMHAVFKSMLFLCAGYVIHSFNGIQDIRMLGSFFKSSPMISSCMMISILSLVGFPFIGGFYSKDLIIEIFLFKMNNMVLLLIFILGLVFSFLYCFRLIYMIMMKGNLNSFLVKVKFDFFMYFSIMLLCILLIVMGNWFNLILMWNFNEVFISKYEKWFFMMLVLFLMYMYMYIKNMNINSDFFFKIWYLSFLTSYILLLNNNKMLKLSLSDWTWMENFGPSMMKNNFVNLLNFNLWLEKKNIMKILMIMLIFIFTMM

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
OL741735
EMBL· GenBank· DDBJ
UXX50167.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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