A0A977K9B3 · A0A977K9B3_9CREN
- ProteinCrossover junction endodeoxyribonuclease Hjc
- Genehjc
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids153 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are subsequently ligated to produce recombinant products.
Catalytic activity
Cofactor
Note: Binds 1 Mg2+ ion per subunit.
Features
Showing features for binding site, active site, site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | crossover junction DNA endonuclease activity | |
Molecular Function | DNA binding | |
Molecular Function | magnesium ion binding | |
Biological Process | DNA recombination | |
Biological Process | DNA repair |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCrossover junction endodeoxyribonuclease Hjc
- EC number
- Short namesHjc
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Desulfurococcales > Desulfurococcaceae > Ignicoccus
Accessions
- Primary accessionA0A977K9B3
Proteomes
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length153
- Mass (Da)17,385
- Last updated2023-02-22 v1
- Checksum09FC739B0D8698DB
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP006868 EMBL· GenBank· DDBJ | UXD21385.1 EMBL· GenBank· DDBJ | Genomic DNA |