A0A977K961 · A0A977K961_9CREN
- ProteinL-aspartate dehydrogenase
- GenenadX
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids247 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
Miscellaneous
The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.
Catalytic activity
- L-aspartate + NAD+ + H2O = oxaloacetate + NH4+ + NADH + H+
Pathway
Cofactor biosynthesis; NAD+ biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 112 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 168 | NAD+ (UniProtKB | ChEBI) | |||
Active site | 196 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | aspartate dehydrogenase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Molecular Function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | |
Biological Process | NAD biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameL-aspartate dehydrogenase
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Desulfurococcales > Desulfurococcaceae > Ignicoccus
Accessions
- Primary accessionA0A977K961
Proteomes
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 8-109 | Aspartate/homoserine dehydrogenase NAD-binding | |||
Domain | 146-231 | Aspartate dehydrogenase | |||
Sequence similarities
Belongs to the L-aspartate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length247
- Mass (Da)27,067
- Last updated2023-02-22 v1
- Checksum006ECCD0996D91E7
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP006868 EMBL· GenBank· DDBJ | UXD21246.1 EMBL· GenBank· DDBJ | Genomic DNA |