A0A975IMG6 · A0A975IMG6_LOWBP
- ProteinUridylate kinase
- GenepyrH
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids234 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reversible phosphorylation of UMP to UDP.
Catalytic activity
- ATP + UMP = ADP + UDP
Activity regulation
Inhibited by UTP.
Pathway
Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 8-11 | ATP (UniProtKB | ChEBI) | ||||
Sequence: KLSG | ||||||
Binding site | 50 | ATP (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 54 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 69 | UMP (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 130-137 | UMP (UniProtKB | ChEBI) | ||||
Sequence: LGLSYFST | ||||||
Binding site | 158 | ATP (UniProtKB | ChEBI) | ||||
Sequence: N | ||||||
Binding site | 164 | ATP (UniProtKB | ChEBI) | ||||
Sequence: Y | ||||||
Binding site | 167 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | UMP kinase activity | |
Biological Process | pyrimidine nucleotide biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUridylate kinase
- EC number
- Short namesUK
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Mycoplasmatota > Mollicutes > Acholeplasmatales > Acholeplasmataceae > Candidatus Phytoplasma > 16SrVIII (Loofah witches'-broom group)
Accessions
- Primary accessionA0A975IMG6
Proteomes
Subcellular Location
Interaction
Subunit
Homohexamer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 3-211 | Aspartate/glutamate/uridylate kinase | ||||
Sequence: KRILLKLSGEALKGKNFNIDPQTVKIIAEEIKEIKDLGIEIIIIVGAGNIWRGLLGEKLGMVRSQSDYMGMLGTIINSLALQDALNHLKVETRVMTAFPVTSIAEPYIKERANRHLNKNRVVILGAGLGLSYFSTDTAAALRSTELNVDVILMAKNGVQGVYTKDPKKHKDAVLLKKIKYKDIIYQRLNIMDVTAVSLCWENGIDILVF |
Sequence similarities
Belongs to the UMP kinase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length234
- Mass (Da)25,987
- Last updated2023-02-22 v1
- Checksum9F098D3208DDFF9D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP054393 EMBL· GenBank· DDBJ | QTX03139.1 EMBL· GenBank· DDBJ | Genomic DNA |