A0A975FJ86 · A0A975FJ86_LOWBP

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site212Zn2+ 1 (UniProtKB | ChEBI)
Binding site214Zn2+ 1 (UniProtKB | ChEBI)
Binding site226Zn2+ 1 (UniProtKB | ChEBI)
Binding site229Zn2+ 1 (UniProtKB | ChEBI)
Binding site601Mg2+ (UniProtKB | ChEBI)
Binding site603Mg2+ (UniProtKB | ChEBI)
Binding site605Mg2+ (UniProtKB | ChEBI)
Binding site988Zn2+ 2 (UniProtKB | ChEBI)
Binding site1062Zn2+ 2 (UniProtKB | ChEBI)
Binding site1069Zn2+ 2 (UniProtKB | ChEBI)
Binding site1072Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionmagnesium ion binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC
    • ORF names
      LFWB_2770

Organism names

  • Taxonomic identifier
  • Strain
    • NCHU2019
  • Taxonomic lineage
    Bacteria > Mycoplasmatota > Mollicutes > Acholeplasmatales > Acholeplasmataceae > Candidatus Phytoplasma > 16SrVIII (Loofah witches'-broom group)

Accessions

  • Primary accession
    A0A975FJ86

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain375-655RNA polymerase N-terminal

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,366
  • Mass (Da)
    156,569
  • Last updated
    2023-02-22 v1
  • Checksum
    281E491616D7AB13
MELEKKIKDLSVSESTLESLKLIEIHCLKDFNSYTLKELKSLLNENTFSEIIPILREYYLPQKLENLNLEPDVISILLNNQINNCFTLLYTDLDILYKLFENENLSFYKAIEDIFILYNKKPKAKNDVYEDVIKEQHNETTKNVSKWFSSQKKYGSREYEHFKIRLASPHEIRQWSYGEIVNYETINYRTTKPEFGGLFCPRIFGPTKDLTCFCVKKKVLKKFQICPRCGVEITEQKVRRERMGHIELAAPIVHTWYLNSSPSRLAVFLGIKTKELSEIVYYASYIFISPGPTKFKKKDIISEMQYGILLEEYGDTFVALTGAEAIKKLLEELNLDAKIAELRKVLKNISKQKRDSIIKRLDILTSFNQSDNKPEWMVIDVLPVLPADLRPIVPLDGGRFATTDINDLYRRILNRNNRLKKQIKQNAPRLIIKNEKRMLQESVDSLFDNVKVNKKNNFNIEKSKTLKSLSEILRGKQGRFRQNLLGKRVDYSGRSVIIVGPELKIHQCGLPRIMAVILFKPFILNKLQEAKGIDKKSATVLYEKMDEYVFNVLEEVVKEHPVLLNRAPTLHRLGIQAFEPKLIDGKAIKLHPLVTPAFNADFDGDQMAVYLPLSIEAQAEARLLMLISNNILDPKNGNPVLFPSQDMVLGNYYLTIEEKRDRILEGFDAEERTKQHQYKHRNEGKIFFDLKEAKLSFYNKEIHLHTRILVKAVNVTSRFMEEQKNKYLVTTLGKLIFNSILPSDFVYIQEPTVFNLEVKTPDIYFISKGQDPTKYLCEANYIEPFKKRFLSMIINRVFNESNITETSQMLDNIKDLGFKYSTIAGITISHSDINVYSKKEELLEVVENKIIEIENFYNRGFLTALEKKNLVIQEWKIVREQIQEGLMKEFNKDNNLFMISDSGARGNTSNFSQLSGMRGLMNSPKGEILEIPVKTSFKEGLTVSEFFISTHGARKVSTDTALKTAESGYLTRRLIDVAQDNIITKEDCGSDKGSYIEAIERDGKIIISLEQRIFSRYTAEDIIHPITKKIIVAKNELLYQKNIEQIIEANIKKVKIRNTLCCNSEFGFCIKCYGLNLTNNKKVEIGEAVGVIAAQSIGEPGTQLTMRTFHTGGVLAVSDITQGLPRIQELFEARKPKGKSIISEYDGIVKEIKNINSSLPRIVISPNFDPKEEIIYDVYSNAEILVQKNMKVKTGQQLTSGSIDLRELLRVTDVETTQKYILEEVQKVYQSQSVSINDKHIEIIVRQMFKQILIIFEGDTSFLPGTETSIKEFKRVNLQMLEQNKKMAVGRPVLLGITRSALKSDSFLSSASFQETTKILIDAAIKGQSDPLYGLKENAIIGGLIPAGTGILESVDFKYPRDKDNK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP054393
EMBL· GenBank· DDBJ
QTX02847.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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