A0A974DS51 · A0A974DS51_XENLA
- ProteinMetalloendopeptidase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1007 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site, active site.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular space | |
Molecular Function | calcium ion binding | |
Molecular Function | metalloendopeptidase activity | |
Molecular Function | serine-type endopeptidase activity | |
Molecular Function | zinc ion binding | |
Biological Process | proteolysis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMetalloendopeptidase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus
Accessions
- Primary accessionA0A974DS51
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-19 | |||||
Sequence: MNMPSWLIFLLTGWTFCDK | ||||||
Chain | PRO_5038164187 | 20-1007 | Metalloendopeptidase | |||
Sequence: LCVCVGLDYDYTNFDNEEEKNEAIDYKDPCKAVVFWGDIALDEEDLKMFHIDRTIDLTQHSNEKLGHTTGGLEEHDLSKKKGALYQLIERIRRFGSGQENTTANSQKVDNNQSGKSKKIRIPRAATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERTDEESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVTIIRENIQPGQEYNFLKMEPGEVHSLGESYDFDSIMHYARNTFSRGMFLDTILPSRDENGLRPPIGQRTRLSKGDIAQARKLYRCPACGETLQESTGNFSSPGFPNGYPSYTHCIWRISVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGFWKKSPLLGRFCGDKLPDVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAICGGEIHKDAGQIQSPNYPDDYRPLKECVWKITVAENYNVGLTFQAFEIERHDNCAYDYLEVRDGSSENSPLIGHFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFLKEEDECARPDNGGCEQRCVNTLGSYKCSCDPGYELAPDKKSCEAACGGLLTKLNGTITTPAWPKEYPPNKNCVWQVVAPSQYRISMKFDYFELEGNEVCKYDYVEVRSGLSSDSKLHGKFCGTEVPEVITSQFNNMRIEFKSDNTVSKKGFRAHFFSDKDECSKDNGGCQHECINTIGSYVCQCRNGFVLHDNKHDCKEAECEHRIHSSNGVITSPNWPDKYPSRKECTWEISATPGHRVKLSFSEFEIEQHQECAYDHLEVFDGETEKSSILGRLCGSKVPEPLVATGNEMFIRFVSDASVQRKGFQATHSTECGGRLKAEAKPRDLFSHAQFGDNNYPVQADCEWILVTERGLRIELNFQTFEVEEEADCGYDFMELFDGHDASAMRLGRFCGSGPPEEIVSTGDAVLIHFHTDDTISKKGFHIRYRSVKYQDILHTK | ||||||
Disulfide bond | 205↔227 | |||||
Sequence: CGCCSYVGRRGNGPQAISIGKNC | ||||||
Disulfide bond | 207↔208 | |||||
Sequence: CC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 117-136 | Polar residues | ||||
Sequence: QENTTANSQKVDNNQSGKSK | ||||||
Region | 117-139 | Disordered | ||||
Sequence: QENTTANSQKVDNNQSGKSKKIR | ||||||
Domain | 143-342 | Peptidase M12A | ||||
Sequence: AATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFIERTDEESYIVFTYRPCGCCSYVGRRGNGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVTIIRENIQPGQEYNFLKMEPGEVHSLGESYDFDSIMHYARNTFSRGMFLDTILPSRDENGLRPPIGQRTRLSKGDIAQARKLYRCP | ||||||
Domain | 344-456 | CUB | ||||
Sequence: CGETLQESTGNFSSPGFPNGYPSYTHCIWRISVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGFWKKSPLLGRFCGDKLPDVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI | ||||||
Domain | 457-569 | CUB | ||||
Sequence: CGGEIHKDAGQIQSPNYPDDYRPLKECVWKITVAENYNVGLTFQAFEIERHDNCAYDYLEVRDGSSENSPLIGHFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFLKE | ||||||
Domain | 569-610 | EGF-like | ||||
Sequence: EEDECARPDNGGCEQRCVNTLGSYKCSCDPGYELAPDKKSCE | ||||||
Domain | 613-725 | CUB | ||||
Sequence: CGGLLTKLNGTITTPAWPKEYPPNKNCVWQVVAPSQYRISMKFDYFELEGNEVCKYDYVEVRSGLSSDSKLHGKFCGTEVPEVITSQFNNMRIEFKSDNTVSKKGFRAHFFSD | ||||||
Domain | 725-765 | EGF-like | ||||
Sequence: DKDECSKDNGGCQHECINTIGSYVCQCRNGFVLHDNKHDCK | ||||||
Domain | 769-881 | CUB | ||||
Sequence: CEHRIHSSNGVITSPNWPDKYPSRKECTWEISATPGHRVKLSFSEFEIEQHQECAYDHLEVFDGETEKSSILGRLCGSKVPEPLVATGNEMFIRFVSDASVQRKGFQATHSTE | ||||||
Domain | 882-998 | CUB | ||||
Sequence: CGGRLKAEAKPRDLFSHAQFGDNNYPVQADCEWILVTERGLRIELNFQTFEVEEEADCGYDFMELFDGHDASAMRLGRFCGSGPPEEIVSTGDAVLIHFHTDDTISKKGFHIRYRSV |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,007
- Mass (Da)114,327
- Last updated2023-02-22 v1
- Checksum6D6117BBFBC2C518
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 117-136 | Polar residues | ||||
Sequence: QENTTANSQKVDNNQSGKSK |