A0A974CYT8 · A0A974CYT8_XENLA
- ProteinPeroxidase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1464 (go to sequence)
- Protein existencePredicted
- Annotation score3/5
Function
Catalytic activity
- hypobromite + L-tyrosyl-[protein] + H+ = 3-bromo-L-tyrosyl-[protein] + H2OThis reaction proceeds in the forward direction.
- L-lysyl-[collagen] + L-methionyl-[collagen] + H2O2 = [collagen]-L-lysyl-N-S-L-methionyl-[collagen] + 2 H2O + H+This reaction proceeds in the forward direction.
- L-tyrosyl-[protein] + bromide + H2O2 + H+ = 3-bromo-L-tyrosyl-[protein] + 2 H2OThis reaction proceeds in the forward direction.
- bromide + H2O2 = hypobromite + H2OThis reaction proceeds in the forward direction.
- L-lysyl-[collagen] + L-methionyl-[collagen] + hypobromite = [collagen]-L-lysyl-N-S-L-methionyl-[collagen] + bromide + H2O + H+This reaction proceeds in the forward direction.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 1070 | Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular space | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Molecular Function | peroxidase activity | |
Biological Process | response to oxidative stress |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended namePeroxidase
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus
Accessions
- Primary accessionA0A974CYT8
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-32 | ||||
Chain | PRO_5037478419 | 33-1464 | Peroxidase | ||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias, coiled coil.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 243-331 | Ig-like | |||
Domain | 339-425 | Ig-like | |||
Domain | 430-517 | Ig-like | |||
Domain | 522-607 | Ig-like | |||
Region | 1332-1364 | Disordered | |||
Compositional bias | 1344-1364 | Polar residues | |||
Coiled coil | 1375-1402 | ||||
Domain | 1399-1457 | VWFC | |||
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,464
- Mass (Da)164,735
- Last updated2023-02-22 v1
- MD5 Checksum399450BBC0A9AA7C07E31E62EAED7F25
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1344-1364 | Polar residues | |||
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM004474 EMBL· GenBank· DDBJ | OCT81192.1 EMBL· GenBank· DDBJ | Genomic DNA |