A0A974CV31 · A0A974CV31_XENLA

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site, active site.

170550100150200250300350400450500550600650700
Type
IDPosition(s)Description
Binding site59Zn2+ (UniProtKB | ChEBI); catalytic
Binding site157Zn2+ (UniProtKB | ChEBI); catalytic
Active site158
Binding site161Zn2+ (UniProtKB | ChEBI); catalytic
Binding site167Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Functionmetalloendopeptidase activity
Molecular Functionzinc ion binding
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Meprin A subunit
  • EC number
  • Alternative names
    • Endopeptidase-2

Gene names

    • ORF names
      XELAEV_18030157mg

Organism names

  • Taxonomic identifier
  • Strain
    • J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    A0A974CV31

Proteomes

Subcellular Location

Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane680-702Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-21
ChainPRO_503815840722-705Meprin A subunit

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain68-262Peptidase M12A
Domain269-433MAM
Domain431-596MATH
Domain632-672EGF-like

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    705
  • Mass (Da)
    79,979
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    DA49D5B7AAAD81B8D9E79405D5070ECD
MGLQGSLQLCSLLTLVVGLAALSINHRPQKLGNDADAGERREDIPQINLESGLDLFEGDIVLTPQSRNALRDDKYRWSFPIPYILADNLGLNAKSVILKTFEMFRLKSCVDFKPYEGEPTYIHFQKFGGCWSMVGDLKTGQNLSIGERCDYKAIVEHEILHALGFYHEQSRSDRDDYVKIWWDEITSGLEHNFNKYENDFITDLNTPYDYESVMHYGPLSFNKNENVPTITAKIEAFNDIIGQRLDFSEIDLERLNRMYNCTASHTLLDQCSFEFINICGMIQGTNDNADWVHMMSEPGLEDHTIAGGCQDAGYFMFFDTHSGPIGSTGLLESRILYPKRSEQCLQFFYKMERNSQDKLVIWLRIDDGAGNVRKMRKIHTIYGDRDNKWKIAHVTLNADKKFRYVFQGVHVNNKTRGGILLDDISLTETPCPNAVWQVRDFSQILESTTKGDRFMSNCFTSPEGYGYAVSIYPHGQESSPYVNYTGISFHMCSGEDDDVMEWPALNRQAIITILDQDPNVQLRMSSSRSFTTLSSQVIESMNNISRWERPSLIGKYDVTCDCYRTLDFGWSTFISHSQLHRRSFLKNDNLILFVDFEDLAFLSKTEVPIKAAAPREQEVVLERSKRSPQHFGETLCDPNPCLNGGVCVQEKGKASCRCSSSQAFFYAGEQCESMKMHGNVLGMLIGGGAGAIALTMAILAIISRR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM004475
EMBL· GenBank· DDBJ
OCT79061.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help