A0A974CBL7 · A0A974CBL7_XENLA

Function

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Features

Showing features for active site, binding site.

1722100200300400500600700
Type
IDPosition(s)Description
Active site350Proton acceptor
Binding site358Zn2+ (UniProtKB | ChEBI)
Binding site361Zn2+ (UniProtKB | ChEBI)
Binding site382Zn2+ (UniProtKB | ChEBI)
Binding site385Zn2+ (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnuclear inner membrane
Cellular Componentnucleoplasm
Cellular ComponentrDNA heterochromatin
Molecular Functionmetal ion binding
Molecular FunctionNAD+ binding
Molecular FunctionNAD-dependent histone deacetylase activity
Molecular Functionp53 binding
Molecular Functiontranscription corepressor activity
Molecular Functiontransferase activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Deacetylase sirtuin-type domain-containing protein

Gene names

    • Name
      sirt1.S
    • ORF names
      XELAEV_18037008mg

Organism names

  • Taxonomic identifier
  • Strain
    • J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus

Accessions

  • Primary accession
    A0A974CBL7

Proteomes

Organism-specific databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region30-95Disordered
Compositional bias75-89Polar residues
Domain223-483Deacetylase sirtuin-type
Compositional bias573-588Polar residues
Region573-597Disordered
Compositional bias644-664Polar residues
Region644-680Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    722
  • Mass (Da)
    79,756
  • Last updated
    2023-02-22 v1
  • MD5 Checksum
    D73B867266B6BDD1619BBE7C1C3371C1
MGDSFSGSGKMADSDRVGFPIAGAVLAVSKENGEPLSKRLRLDDTGGGDGQLVGAESEGKAALPPIAASLQEEGEASSAMESKSRAHSGSGFQGLPLEKRQLGTYLAQGQEEGGADEMPNGDLSDQTIDYGGSIHLDDDLAGGFHSCDSDDDDGTSHASSSDWAPRPCIGPYTFVQRHLMMGTDPRTILKDLLPDPVAPSELDDMTLWQIVINILSDPPKRKKRKDINTIDDVVKLLQESKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPNPQAMFDIEYFRKDPRPFFKFAKEIFPGQFQPSLCHRFIAMLDKEEKLLRNYTQNIDTLEQVAGIEKIIQCHGSFAEASCLVCKYKVDCEAVREDIFNQIVPRCPRCSPDEPLAIMKPDIVFFGENLPEQFHRAMKYDKNEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLRFDIELLGDCDVIINELCQRLDGKYSQLCTNSLKLSQITEKPPQIHKGFLTSPETISSTDLNTGQTAELQSELQETALISASNTTCSMEKPKEDSKISHSCTVENLEVFKEINAQTLKGSSQTETQPTNEKNRETTDKDTDIVSIKDLESKYTKEQISKHLDRTQFLFLTPNRYIFHGAEVFSDSDEDLTSSSCGTNSDSESLLSPSLHEPIEEDSETEECFHAKCENETDTDNRADIEKEAQSVVLYESDDLLGNDGTTMNL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias75-89Polar residues
Compositional bias573-588Polar residues
Compositional bias644-664Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM004479
EMBL· GenBank· DDBJ
OCT70087.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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