A0A974CB89 · A0A974CB89_XENLA
- ProteinTriacylglycerol lipase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids474 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- 1,2,3-tri-(9Z-octadecenoyl)-glycerol + H2O = di-(9Z)-octadecenoylglycerol + (9Z)-octadecenoate + H+This reaction proceeds in the forward direction.
- 1,2,3-tributanoylglycerol + H2O = dibutanoylglycerol + butanoate + H+This reaction proceeds in the forward direction.
- 1,2-di-(9Z-octadecenoyl)-glycerol + H2O = (9Z-octadecenoyl)-glycerol + (9Z)-octadecenoate + H+This reaction proceeds in the forward direction.
- all-trans-retinyl hexadecanoate + H2O = all-trans-retinol + hexadecanoate + H+This reaction proceeds in the forward direction.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 171 | Nucleophile | |||
Active site | 194 | Charge relay system | |||
Binding site | 208 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 210 | Ca2+ (UniProtKB | ChEBI) | |||
Binding site | 213 | Ca2+ (UniProtKB | ChEBI) | |||
Active site | 281 | Charge relay system | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | extracellular space | |
Molecular Function | metal ion binding | |
Molecular Function | triacylglycerol lipase activity | |
Biological Process | lipid catabolic process |
Keywords
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameTriacylglycerol lipase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Amphibia > Batrachia > Anura > Pipoidea > Pipidae > Xenopodinae > Xenopus > Xenopus
Accessions
- Primary accessionA0A974CB89
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-17 | ||||
Chain | PRO_5038168375 | 18-474 | Triacylglycerol lipase | ||
Disulfide bond | 451↔467 | ||||
Keywords
- PTM
Interaction
Subunit
Forms a 1:1 stoichiometric complex with (pro)colipase/CLPS.
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length474
- Mass (Da)52,744
- Last updated2023-02-22 v1
- ChecksumBD81E3B90826C691
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CM004479 EMBL· GenBank· DDBJ | OCT69732.1 EMBL· GenBank· DDBJ | Genomic DNA |