A0A970N528 · A0A970N528_9FIRM

  • Protein
    Polyamine aminopropyltransferase
  • Gene
    speE
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site31S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site62spermidine (UniProtKB | ChEBI)
Binding site86spermidine (UniProtKB | ChEBI)
Binding site106S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Binding site137-138S-methyl-5'-thioadenosine (UniProtKB | ChEBI)
Active site155Proton acceptor
Binding site155-158spermidine (UniProtKB | ChEBI)
Binding site162S-methyl-5'-thioadenosine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionspermidine synthase activity
Biological Processspermidine biosynthetic process

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Polyamine aminopropyltransferase
  • Alternative names
    • Putrescine aminopropyltransferase
      (PAPT
      )
    • Spermidine synthase
      (SPDS
      ; SPDSY
      ) (EC:2.5.1.16
      ) . EC:2.5.1.16 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      speE
    • ORF names
      GX136_00060

Organism names

Accessions

  • Primary accession
    A0A970N528

Proteomes

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain2-237PABS

Sequence similarities

Belongs to the spermidine/spermine synthase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    286
  • Mass (Da)
    33,101
  • Last updated
    2023-02-22 v1
  • Checksum
    50B67B3BF9758774
MELWYSERHTPNVKLSIKVDRQIFSGKSDFQSIEVMESPEFGRFLTIDGYMMLTEKDEFIYHEMIVHPAMAVHPEAKRILVIGAGDGGVVRELVNYPFVEHIDLVDIDEMVIEVCKKYLPQTACCLDDERVSIHIQDGLKFIRRCKDEYDVIIVDSTDPFGPGEGLFTKEFYGNCFKALKEDGIMVNQHESPFYPEDAIAMQRAHKRIVESFPISRVYQAHIPTYPSGHWLFGFASKKYHPIFDFDAGRWRGLGIKTRYYNTQLHVGSFALPNYVEELLEDVEEVE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAAYKB010000003
EMBL· GenBank· DDBJ
NLN80934.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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