A0A960AI80 · A0A960AI80_9ACTN

  • Protein
    K(+)-insensitive pyrophosphate-energized proton pump
  • Gene
    hppA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for site.

TypeIDPosition(s)Description
Site502Determinant of potassium independence

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functiondiphosphate hydrolysis-driven proton transmembrane transporter activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmagnesium ion binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    K(+)-insensitive pyrophosphate-energized proton pump
  • EC number
  • Alternative names
    • Membrane-bound proton-translocating pyrophosphatase
    • Pyrophosphate-energized inorganic pyrophosphatase
      (H(+)-PPase
      )

Gene names

    • Name
      hppA
    • ORF names
      KDC40_06235

Organism names

Accessions

  • Primary accession
    A0A960AI80

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane20-39Helical
Transmembrane71-89Helical
Transmembrane101-124Helical
Transmembrane145-171Helical
Transmembrane183-201Helical
Transmembrane249-267Helical
Transmembrane273-293Helical
Transmembrane305-329Helical
Transmembrane360-382Helical
Transmembrane394-412Helical
Transmembrane418-436Helical
Transmembrane443-463Helical
Transmembrane562-592Helical
Transmembrane632-648Helical
Transmembrane720-739Helical
Transmembrane745-764Helical

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    782
  • Mass (Da)
    80,000
  • Last updated
    2023-02-22 v1
  • Checksum
    E99C2E9B9EB432EA
MSAGTVAASVVTLTGGSYTTVIVVALIALLALVVAGLLVREVLAASEGTDNMKSIAEAVQEGAAAYLSRQFRTLSIFAVIVFFVLFLLPAETTNERIGRSIFFLVGAVFSAVTGYVGMWLAVRANVRVAAAAREGKPGETKAMRIAFRTGGVAGMFTVGLGLLGAAIVVLVYKGEAPKVLEGFGFGAALLAMFMRVGGGIFTKAADVGADLVGKVEQGIPEDDPRNAATIADNVGDNVGDCAGMAADLFESYAVTLVAALILGQAALGSLGLVIPLVIPAIGVLTAMIGIFAVSPRANDRSGMAAINRGFFISAIISAVLVTIAAFIWLPDRLIKLTDFELVRDRLGLSVTTLEVLNPRFLVIAAVLIGIILAAAIQQLTGYFTETNRKPVDDVARTSLTGPATVILSGISLGLESAVYSALLIGAAVYGAFLLGAGSITLSLFAVALAGTGLLTTVGVIVAMDTFGPVSDNAQGIAEMSGDVEGEGAQVLTSLDAVGNTTKAITKGIAIATAVLAATALFGSFRDAVQQAAAQAGDALQGLSVQDATQYLGILDVSNPRNLVGLLIGASVVFLFSGLAINAVTRAAGAIIFEVRRQFKEHPGIMEGTEKPEYGKVVDICTRDSLRELSTPGLLAILTPIAVGFGLGIGALGSFLAGTIATGALMAVFLANSGGAWDNAKKYVEDGNHGGKGSEAHEATVIGDTVGDPFKDTAGPAINPLIKVMNLVSLLIAPAVVSMFLDDNALRWAIALGALAIVVGAVVITKRRPIAVSPQEIAAAEAQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JAGQUD010000018
EMBL· GenBank· DDBJ
MCB0898408.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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